The journey to diagnosis and care of functional neurological disorder (FND). [PDF]
Pritomanova I +10 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Sex-Specific BMI Trajectories in Young People With Type 1 Diabetes: A 20-Year Retrospective Regional Audit. [PDF]
Oliver-Rose C +5 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A Qualitative Analysis of Pediatricians' Perspectives Regarding Barriers, Facilitators, and Strategies for Providing Timely Autism Spectrum Disorder Screening and Diagnosis. [PDF]
Mathur M +7 more
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Diagnostic yield or diagnostic accuracy estimation? [PDF]
Fruchter O.
europepmc +1 more source
Dynamic cytogenetic evolution in multiple myeloma: prognostic implications from diagnosis to first relapse. [PDF]
Chen Q +7 more
europepmc +1 more source

