Results 301 to 310 of about 12,440,936 (400)

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Criteria for designing integrated diagnosis interventions in low resource settings at the primary care level: a Delphi consensus study. [PDF]

BMC Health Serv Res
Gwaza GP, Plüddemann A, MacBain McCall M, Dittrich S, Heneghan C.   +4 more
europepmc   +1 more source

Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels. Methods Patients with FIRES admitted to the Intensive Care Unit (ICU) of Beijing Children's Hospital were retrospectively ...
Yushan He, Jie Wu, Chaonan Fan, Zheng Li, Jun Liu, Kechun Li, Quan Wang, Suyun Qian   +7 more
wiley   +1 more source

A reconsidered diagnosis in an unresolving myocarditis-a case report. [PDF]

Eur Heart J Case Rep
Woolfenden B, Cawley C, Ward D.
europepmc   +1 more source

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source

GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction during Routine Tumor Profiling. [PDF]

Cancer Res Commun
Ghani H, Helmstetter A, Ribeiro JR, Maney T, Rock S, Feldman RA, Swensen J, Abdulla F, Spetzler DB, Florento E, Vanderwalde AM, Pittman P, Radovich M, Hechtman J, Bales C, Sledge GW, George MM, Bryant D, Abraham JP, Oberley MJ.   +19 more
europepmc   +1 more source

Long‐Term Temporal Profile of Motor Recovery After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Limited data is available to describe the temporal profile of long‐term recovery over 1 year after the stroke in patients with spontaneous intracerebral hemorrhage (ICH). Methods A registered multicentral cohort was conducted to consecutively include non‐herniated supratentorial ICH patients from November 2013 to January 2023 ...
Yan Zheng, Fu‐Xin Lin, Ling‐Yun Zhuo, Jian‐Cai Chen, Xin Ge, Xiang‐Lin Chen, Xue‐Jiao Wang, Zhi‐Gang Yao, You‐Liang Tong, Bo Xie, Bai‐Hai Guo, Zhao‐Sheng Sun, Zhi‐Hua Tian, Ping Qiu, Xin‐Ru Lin, Qiu He, Shu‐Na Huang, Ke Ma, Fang‐Yu Wang, Huang‐Cheng Shang‐Guan, Wen‐Hua Fang, Deng‐Liang Wang, Ying Fu, Yuan‐Xiang Lin, De‐Zhi Kang   +24 more
wiley   +1 more source

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang, Bowen Ni, Kezhi Wu, Qi Zhang, Jinglin Guo, Runwei Yang, Ziyu Wang, Guozhong Yi, Guanglong Huang, Minyi He, Yimin Xu, Yawei Liu   +11 more
wiley   +1 more source

Adherence to World Cancer Research Fund/American Institute for Cancer Research Guidelines and Mortality among Participants with Colorectal Cancer in the MEC. [PDF]

Cancer Epidemiol Biomarkers Prev
Asiimwe E, Tolstykh I, Chan JM, Kenfield SA, Wilkens LR, Park SY, Le Marchand L, Huang BZ, Haiman CA, Cheng I, Van Blarigan EL.   +10 more
europepmc   +1 more source