Results 61 to 70 of about 8,808,626 (352)

Characteristics and outcomes of diffuse non-midline gliomas with H3F3A gene mutation in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort study

Acta Neuropathologica Communications
Diffuse gliomas with H3F3A gene mutation such as H3.3 K27M and G34R/V are infrequently found in the cerebral hemisphere. These tumors may be called histone H3 K27M-mutant diffuse non-midline gliomas (NDMG) or H3 G34-mutant diffuse hemispheric gliomas ...
Hirokazu Nakatogawa, Junya Fukai, Hiroshi Kawaji, Nobuhide Hayashi, Ema Yoshioka, Yoshinori Kodama, Kosuke Nakajo, Takehiro Uda, Yoshiki Arakawa, Shigeki Takada, Noriyuki Kijima, Kenichi Ishibashi, Takeshi Okuda, Yukihiko Sonoda, Shiro Ohue, Hideyuki Arita, Masahide Matsuda, Tadateru Fukami, Takahiro Tomita, Akihiro Inoue, Takamune Achiha, Hideki Kashiwagi, Daisuke Kanematsu, Asako Katsuma, Miho Sumida, Tomoko Shofuda, Masayuki Mano, Manabu Kinoshita, Kanji Mori, Chikanori Inenaga, Yonehiro Kanemura   +30 more
doaj   +1 more source

Learning multiple fault diagnosis [PDF]

, 1991
This paper describes two methods for integrating model-based diagnosis (MBD) and explanation-based learning. The first method (EBL) uses a generate-test-debug paradigm, generating diagnostic hypotheses using learned associational rules that summarize ...
Fattah, Yousri El, O'Rorke, Paul
core  

Analyzing the Triad Diagnosis Requirement for Autism in Arkansas [PDF]

, 2020
Autism Spectrum Disorder (ASD) is a developmental disorder that has steadily increased in incidence and prevalence over the last ten years. While the disorder can be diagnosed as early as two years of age, most children do not receive a diagnosis until ...
Barrientos-Figueroa, Liliana
core   +2 more sources

Characteristics of people living in Italy after a cancer diagnosis in 2010 and projections to 2020 [PDF]

, 2018
BACKGROUND: Estimates of cancer prevalence are widely based on limited duration, often including patients living after a cancer diagnosis made in the previous 5 years and less frequently on complete prevalence (i.e., including all patients regardless of
Botta, Laura, Buzzoni, Carlotta, Caiazzo, Anna Luisa, Candela, Giuseppa, Capocaccia, Riccardo, Caruso, Bianca, Casella, Claudia, Castaing, Marine, De Angelis, Roberta, Falcini, Fabio, Fanetti, Anna Clara, Ferretti, Stefano, Francisci, Silvia, Fusco, Mario, Giacomin, Adriano, Gigli, Anna, Gola, Gemma, Guzzinati, Stefano, Mangone, Lucia, Maso, Luigino Dal, Mazzoleni, Guido, Michiara, Maria, Pala, Filomena, Panato, Chiara, Pannozzo, Fabio, Ricci, Paolo, Rudisi, Giuseppa, Rugge, Massimo, Russo, Antonio Giampiero, Sardo, Antonella Sutera, Sensi, Flavio, Serraino, Diego, Stracci, Fabrizio, Tagliabue, Giovanna, Tisano, Francesco, Tumino, Rosario, Virdone, Saverio, Zorzi, Manuel   +37 more
core   +2 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

A Graphene Oxide-Based Fluorescent Aptasensor for the Turn-on Detection of CCRF-CEM

Nanoscale Research Letters, 2018
A convenient, low-cost, and highly sensitive fluorescent aptasensor for detection of leukemia has been developed based on graphene oxide-aptamer complex (GO-apt).
Jie Tan, Zongqiang Lai, Liping Zhong, Zhenghua Zhang, Rong Zheng, Jing Su, Yong Huang, Panpan Huang, Hui Song, Nuo Yang, Sufang Zhou, Yongxiang Zhao   +11 more
doaj   +1 more source

Forensic and clinical diagnosis in shaken baby syndrome , between child abuse and iatrogenic abuse [PDF]

, 2017
“Shaken baby syndrome” in child abuse cases is a challenge for pediatrician and forensic experts, often a diagnosis of exclusion, with overwhelming moral and legal implications.
Apostol, Irina, Belis, Vladimir, Calota, Relu G., Duncea, Roxana M.   +3 more
core   +6 more sources

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

FEBS Letters, EarlyView.
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio, Sofia Lövestam, Michael A. Metrick II, Thomas Löhr, Peifeng Xu, Nicholas C. T. Gallagher, Bernardino Ghetti, Byron Caughey, Sjors H. W. Scheres, Michele Vendruscolo   +9 more
wiley   +1 more source

Peripartum cardiomyopathy: diagnosis and management [PDF]

, 2017
No abstract ...
Coats, Caroline J., Dalzell, Jonathan R., Jackson, Alice M., Jhund, Pardeep S., Petrie, Mark C., Walker, Niki L.   +5 more
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source