Results 71 to 80 of about 12,810,150 (402)

Family members dealing with childhood cancer : a study on the role of family functioning and cancer appraisal [PDF]

, 2019
Objectives: Childhood cancer is a life-threatening disease that poses significant challenges to the life of the diagnosed child and his/her family members.
Cosyns, Veerle, De Paepe, Annick, Goubert, Liesbet, Morren, Hanne, Norga, Koenraad, Van Schoors, Marieke, Vercruysse, Trui, Verhofstadt, Lesley   +7 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

臨床所見および検査成績からのスコアーによる喘息分類の特徴 [PDF]

, 1992
Twenty six patients with bronchial asthma was classified by clinical symptoms and singns (clinical diagnosis), and the classification by clinical diagnosis was compared with the classification by a score calculated from clinical findings and examinations
Honke, Naoko, Kimura, Ikuro, Kitani, Hikaru, Kusaura, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Okazaki, Morihiro, Okuda, Hiroyuki, Takatori, Akimasa, Tanimizu, Masakuni, Tanizaki, Yoshiro   +10 more
core   +1 more source

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2012
Authors/Task Force Members: John J.V. McMurray (Chairperson) (UK)*, Stamatis Adamopoulos (Greece), Stefan D. Anker (Germany), Angelo Auricchio (Switzerland), Michael Bohm (Germany), Kenneth Dickstein (Norway), Volkmar Falk (Switzerland), Gerasimos ...
J. McMurray, S. Adamopoulos, S. Anker, A. Auricchio, M. Böhm, K. Dickstein, V. Falk, G. Filippatos, C. Fonseca, M. Gómez-Sánchez, T. Jaarsma, L. Køber, G. Lip, A. Maggioni, A. Parkhomenko, B. Pieske, B. Popescu, P. Rønnevik, F. Rutten, J. Schwitter, P. Seferovic, J. Stȩpińska, P. Trindade, A. Voors, F. Zannad, A. Zeiher, J. Bax, H. Baumgartner, C. Ceconi, V. Dean, C. Deaton, R. Fagard, C. Funck-Brentano, D. Hasdai, A. Hoes, P. Kirchhof, J. Knuuti, P. Kolh, T. McDonagh, C. Moulin, Ž. Reiner, U. Sechtem, P. Sirnes, M. Tendera, A. Torbicki, A. Vahanian, S. Windecker, L. A. Bonet, P. Avraamides, Hisham A. Ben Lamin, M. Brignole, A. Coca, Peter Cowburn, H. Dargie, P. Elliott, F. Flachskampf, Guido Francesco Guida, S. Hardman, B. Iung, B. Merkely, C. Mueller, J. Nanas, O. Nielsen, S. Ørn, J. Parissis, P. Ponikowski   +65 more
semanticscholar   +1 more source

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

Nature Reviews Clinical Oncology, 2020
In response to major changes in diagnostic algorithms and the publication of mature results from various large clinical trials, the European Association of Neuro-Oncology (EANO) recognized the need to provide updated guidelines for the diagnosis and ...
M. Weller, M. J. van den Bent, M. Preusser, É. Le Rhun, J. Tonn, G. Minniti, M. Bendszus, C. Balañà, O. Chinot, L. Dirven, P. French, M. Hegi, A. Jakola, M. Plattén, P. Roth, R. Rudà, S. Short, M. Smits, M. Taphoorn, A. von Deimling, M. Westphal, R. Soffietti, G. Reifenberger, W. Wick   +23 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Diagnosis of central nervous system lymphoma via cerebrospinal fluid cytology: a case report

BMC Neurology, 2019
Background Primary central nervous system lymphoma (PCNSL) is the most prevalent brain, spinal cord, eyes, and leptomeningeal lymphoma. It is often misdiagnosed due to an unspecific presentation or unavailable biopsy and results in a poor prognosis ...
Hui Zhao, Miao Ma, Limin Zhang, Guanghui Zheng, Hong Lv, Jie Liu, Xiao Li, Bei Song, Guojun Zhang   +8 more
doaj   +1 more source

Clinical and molecular cytogenetic findings and pregnancy outcomes of fetuses with isochromosome Y

Molecular Cytogenetics, 2022
Background The mosaic forms and clinical phenotypes of fetuses with isochromosome Y are difficult to predict. Therefore, we summarized the cases of nine fetuses with isochromosome Y identified in prenatal diagnosis with a combination of molecular ...
Yiqun He, Li Guo, Laiping Zheng, Congmian Ren, Ting Wang, Jian Lu   +5 more
doaj   +1 more source

Sarcopenia: European consensus on definition and diagnosis

Age and Ageing, 2010
The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia. EWGSOP included representatives from four participant organisations, i.e.
A. Cruz-Jentoft, J. Baeyens, J. Bauer, Y. Boirie, T. Cederholm, F. Landi, F. Martin, J. Michel, Y. Rolland, S. Schneider, E. Topinkova, M. Vandewoude, M. Zamboni   +12 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source