Results 11 to 20 of about 2,850,943 (269)

Development and validation of a novel circular RNA as an independent prognostic factor in acute myeloid leukemia

BMC Medicine, 2021
Background Although there are many clinical and molecular biomarkers in acute myeloid leukemia (AML), the novel and reliable biomarkers are still required to predict the overall survival at the time of disease diagnosis.
Jinghan Wang, Jiajia Pan, Shujuan Huang, Fenglin Li, Jiansong Huang, Xia Li, Qing Ling, Wenle Ye, Yungui Wang, Wenjuan Yu, Jie Jin   +10 more
doaj   +1 more source

Comparison of the inoculum effect of in vitro antibacterial activity of Imipenem/relebactam and Ceftazidime/avibactam against ESBL-, KPC- and AmpC-producing Escherichia coli and Klebsiella pneumoniae

Annals of Clinical Microbiology and Antimicrobials, 2023
Objective To evaluate effect of inoculum size of extended-spectrum β-Lactamase (ESBL)-producing-, AmpC-producing-, and KPC-producing Escherichia coli and Klebsiella pneumoniae on the in vitro antibacterial effects of imipenem/relebactam (IMR) and ...
Xueting Wang, Luying Xiong, Yuan Wang, Kai Yang, Tingting Xiao, Xiaohui Chi, Tao Chen, Yanzi Zhou, Ping Lu, Dilimulati Dilinuer, Pin Shen, Yunbo Chen, Yonghong Xiao   +12 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor is associated with short-term mortality and enhanced reactive oxygen species production in acute-on-chronic liver failure

BMC Gastroenterology, 2021
Background Acute-on-chronic liver failure (ACLF) is a comprehensive syndrome characterized by an acute deterioration of liver function and high short-term mortality rates in patients with chronic liver disease.
Yunyun Wang, Fengtian Wu, Chao Chen, Lichen Xu, Wei Lin, Chunhong Huang, Ying Yang, Shanshan Wu, Jinjin Qi, Hanqin Cao, Guojun Li, Meng Hong, Haihong Zhu   +12 more
doaj   +1 more source

Role of mesenchymal stem cells, their derived factors, and extracellular vesicles in liver failure

Stem Cell Research & Therapy, 2017
Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver failure.
Jie Wang, Panpan Cen, Jiajia Chen, Linxiao Fan, Jun Li, Hongcui Cao, Lanjuan Li   +6 more
doaj   +1 more source

Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury

Cell Death and Disease, 2022
Schematic diagram of the protective effect of MSC-derived exosomes on maintaining SLC7A11 function during ferroptosis involved in CCl4-induced ALI.
Feiyan Lin, Wenyi Chen, Jiahang Zhou, Jiaqi Zhu, Qigu Yao, Bing Feng, Xudong Feng, Xiaowei Shi, Qiaoling Pan, Jiong Yu, Lanjuan Li, Hongcui Cao   +11 more
doaj   +1 more source

Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects

Stem Cell Research & Therapy, 2020
Background Idiopathic pulmonary fibrosis is a kind of diffuse interstitial lung disease, the pathogenesis of which is unclear, and there is currently a lack of good treatment to improve the survival rate.
Xin Chen, Yi Wu, Yanling Wang, Lijun Chen, Wendi Zheng, Sining Zhou, Huikang Xu, Yifei Li, Li Yuan, Charlie Xiang   +9 more
doaj   +1 more source

Human placenta mesenchymal stem cell-derived exosomes delay H2O2-induced aging in mouse cholangioids

Stem Cell Research & Therapy, 2021
Background Cholangiocyte senescence is an important pathological process in diseases such as primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC).
Wenyi Chen, Jiaqi Zhu, Feiyan Lin, Yanping Xu, Bing Feng, Xudong Feng, Xinyu Sheng, Xiaowei Shi, Qiaoling Pan, Jinfeng Yang, Jiong Yu, Lanjuan Li, Hongcui Cao   +12 more
doaj   +1 more source

Probiotics may not prevent the deterioration of necrotizing enterocolitis from stage I to II/III

BMC Pediatrics, 2019
Background Probiotic therapy can reduce the incidence of NEC. Therapeutic use of probiotics after NEC diagnosis reduces the severity of NEC in preterm infants or full-term infants is unclear.
Zheng-Li Wang, Li Liu, Xiao-Yu Hu, Lu Guo, Qiu-Yu Li, Yao An, Ya-Jun Jiang, Shi Chen, Xue-Qiu Wang, Yu He, Lu-Quan Li   +10 more
doaj   +1 more source

Reactivation of occult hepatitis B virus infection in a renal transplant recipient

Virology Journal, 2022
We report a case of hepatitis B virus (HBV) reactivation in a renal transplant recipient. Reactivation manifested as an occult infection with detectable HBV-DNA and negativity for hepatitis B surface antigen (HBsAg). The anti-HBs antibody titre was above
Lili Jiang, Huiqi Wang, Yaping Huang, Hanying Liang, Xiaodong Wang, Jun Fan   +5 more
doaj   +1 more source

Pneumonia. Treatment and Diagnosis [PDF]

Annals of the American Thoracic Society, 2014
Pneumonia remains a leading cause of morbidity and mortality despite advances in treatment and therapy. The "Pneumonia: Treatment and Diagnosis" session of the Pittsburgh International Lung Conference examined topics related to improving care of patients with pneumonia.
Joshua T, Mattila, Michael J, Fine, Andrew H, Limper, Patrick R, Murray, Bill B, Chen, Philana Ling, Lin   +5 more
openaire   +2 more sources