Results 201 to 210 of about 5,165,384 (312)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Bidirectional Relationship Between Systemic Immune-Inflammation Index and Postoperative Pneumonia in Elderly Patients Undergoing Colorectal Cancer Surgery: A Retrospective Cohort Study

Clinical Interventions in Aging
Yanmin Wu,1,* Bing Ye,1,* Tiantian Zhao,1,* Peihua Lu2 1Digestive Disease Diagnosis and Treatment Center, Affiliated Hospital of Jiangnan University, Wuxi, People’s Republic of China; 2Department of Oncology, The Affiliated Wuxi ...
Wu Y, Ye B, Zhao T, Lu P
doaj  

Palmoplantar pustulosis: pathogenesis, differential diagnosis, and treatment. [PDF]

J Dtsch Dermatol Ges
Mössner R, Fetter T, Sabat R, Mrowietz U, Cramer N, Wilsmann-Theis D.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Editorial: Sarcoidosis diagnosis and treatment based on etiology. [PDF]

Front Med (Lausanne)
Sawahata M, Eishi Y.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Recent Updates to Diagnosis and Treatment of Spontaneous Intracranial Hypotension. [PDF]

Korean J Radiol
Madhavan AA, Yoon ES, Chazen JL.
europepmc   +1 more source

The Diagnosis and Treatment of Lung Cancer: Methods, evidence and guidance [PDF]

, 2005
Belchamber, C.A., National Collaborating Centre for Acute Care,   +1 more
core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The role of the microbiome in gynecological cancers: implications for diagnosis and treatment. [PDF]

Front Immunol
Oyedokun PA, Oyeleke BT, Akanji OO, Oyelaran AO, O KP, Akanbi GB, Oyedokun PO, Oyedokun MD, Naomi CC, Imoleayo OO, Akhigbe RE.   +10 more
europepmc   +1 more source