ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan +5 more
wiley +1 more source
An evidence-based algorithm for the utility of FDG-PET for diagnosing Alzheimer's disease according to presence of medial temporal lobe atrophy [PDF]
BackgroundImaging biomarkers for Alzheimer's disease include medial temporal lobe atrophy (MTLA) depicted on computed tomography (CT) or magnetic resonance imaging (MRI) and patterns of reduced metabolism on fluorodeoxyglucose positron emission ...
Cam Donaldson +13 more
core +1 more source
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
Parent‐to‐Child Information Disclosure in Pediatric Oncology
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor +12 more
wiley +1 more source
Advanced prospects for management of obstructive sleep apnea: An updated comprehensive review
Obstructive sleep apnea (OSA) is negatively affecting the health of people and their quality of life. This breathing disorder has a multifactorial etiology.
Mohammad Kamran Khan
doaj +1 more source
The adaptive internet application for interpretation of the transformer oil gas chromatographic analysis results [PDF]
This paper describes an adaptive Internet application for the interpretation of the transformer oil gas chromatographic analysis results. The first version of the application is developed by following an evolutionary software development concept.
Polužanski Vladimir +4 more
doaj +1 more source
Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]
Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core +2 more sources
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura +5 more
wiley +1 more source
The Signal Data Explorer: A high performance Grid based signal search tool for use in distributed diagnostic applications [PDF]
We describe a high performance Grid based signal search tool for distributed diagnostic applications developed in conjunction with Rolls-Royce plc for civil aero engine condition monitoring applications.
Austin, Jim +4 more
core +1 more source
CTHRC1 expression is a novel shared diagnostic and prognostic biomarker of survival in six different human cancer subtypes [PDF]
Nuzhat Sial +16 more
openalex +1 more source

