Results 71 to 80 of about 2,687,067 (268)

Nematode Species Identification—Current Status, Challenges and Future Perspectives for Cyathostomins

Frontiers in Cellular and Infection Microbiology, 2017
Human and animal health is globally affected by a variety of parasitic helminths. The impact of co-infections and development of anthelmintic resistance requires improved diagnostic tools, especially for parasitic nematodes e.g., to identify resistant ...
Christina M. Bredtmann, Jürgen Krücken, Jayaseelan Murugaiyan, Tetiana Kuzmina, Georg von Samson-Himmelstjerna   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Warthin tumors – risk factors, diagnostics, treatment

Nowotwory
INTRODUCTION: Warthin tumors are the second most common benign tumor of the salivary gland, located mainly in the parotid glands, sometimes bilaterally. The main risk factor is nicotine addiction. The aim of the study was to present our own experience in
Katarzyna Kolary-Siekierska, Anna Jałocha-Kaczka, Piotr Niewiadomski, Jarosław Miłoński   +3 more
doaj   +1 more source

Comparison of Surface Plasmon Resonance, Resonant Waveguide Grating Biosensing and Enzyme Linked Immunosorbent Assay (ELISA) in the Evaluation of a Dengue Virus Immunoassay

Biosensors, 2013
Two label-free biosensor platforms, Resonance Waveguide Grating (RWG) and Surface Plasmon Resonance (SPR), were used to rank a large panel of anti-dengue virus NS1 antibodies. Dengue non-structural 1 (NS1) protein is an established serological marker for
Joe Buechler, Xiaoyan Che, Jing Jin, Catriona McElnea, Yue Chen, Yuxian Pan, Liwen Qiu, Xixia Ding, Johnny X. Huang, Scott R. Fry, Dongmei Hu, Matthew A. Cooper   +11 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Diagnostic and Management Approach of Obesity with Multiple Complications in a Child: A Case Report

Archives of Pediatric Gastroenterology, Hepatology, and Nutrition
Background: Adults with obesity may already experience obesity during childhood or adolescence, highlighting the critical importance of early intervention. This is particularly concerning given that childhood obesity, a growing component of Indonesia's "
Siti Azura Putri Dilla Sari, Cut Nurul Hafifah   +1 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

A ética da psicanálise e o diagnóstico psiquiátrico-político. Um estudo de caso a partir da biografia de “Jacinta Passos”

Revista Latinoamericana de Psicopatologia Fundamental
Este artigo tem como objetivo apresentar a distinção entre ética e diagnóstico na psicanálise e na psiquiatria, a partir do estudo de caso de Jacinta Passos (1914-1973), militante política e escritora baiana, diagnosticada como esquizofrênica, sendo que ...
Antonio Alberto Peixoto de Almeida, Regina Fabbrini   +1 more
doaj   +1 more source