Results 111 to 120 of about 4,265,853 (264)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

DIAGNOSTIC ACCURACY OF TYPHIDOT IN PATIENTS OF TYPHOID FEVER

Pakistan Armed Forces Medical Journal, 2018
Objective: To assess the diagnostic accuracy of Typhidot test in patients with acute febrile illness taking blood culture as gold standard. Study Design: Cross-sectional validation study.
Hammad Javed, Karamat Hussain, Tariq Bashir, Sana ullah, Umair Ijaz, Ismail Khoso   +5 more
doaj  

Comparing the Diagnostic Accuracy of Direct Digital and Conventional Intraoral Peri-apical Radiographs in Identifying Interdental Bone Loss: An Observational Study

Journal of Pharmacy and Bioallied Sciences
The evaluation of conventional two-dimensional radiography is crucial in making the diagnosis of periodontitis. Radio-visiography (RVG) is one of the digital imaging modalities that have received significant recognition as a replacement for film-based ...
Chakraborty Sankha S, Manohar Balaji, Bhuyan Lipsa, Anupriya CH, Kaur Awneet   +4 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Lung ultrasonography used as a diagnostic test for respiratory disease diagnosis in calves: Systematic review and meta-analysis using a Bayesian latent-class modeling approach

Journal of Dairy Science
: Bovine respiratory disease complex is a common disease that commonly affects calves in the form of bronchopneumonia. There is currently no affordable, perfectly accurate reference standard test, and the routine diagnosis is commonly based on clinical ...
S. Buczinski, V. Gomes, G. Vergnes, M.C. Poirier, S. Owusu-Afryie, J. Berman, N. Dendukuri   +6 more
doaj   +1 more source

nonbinROC: Software for Evaluating Diagnostic Accuracies with Non-Binary Gold Standards [PDF]

ROC analysis is a standard method for estimating and comparing diagnostic tests' accuracies when the gold standard is binary. However, there are many situations when the gold standard is not binary.
Paul Nguyen
core  

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Diagnostic accuracy of computer-aided detection for colorectal polyps of any size, ≤ 5 mm, and 6–9 mm: a meta-analysis

World Journal of Surgical Oncology
Background Although computer-aided detection (CAD) is often used for medical diagnostic purposes, its diagnostic effectiveness in colorectal polyps (CPs) remains uncertain.
Wen Chen, Simeng Li, Zhenheng Wu, Haifen Tan, Fuqian Yu, Dongmei Wang, Xiaodan Lin, Zhigang Chen   +7 more
doaj   +1 more source

Thoracic imaging tests for the diagnosis of COVID-19

, 2021
BACKGROUND: The respiratory illness caused by SARS-CoV-2 infection continues to present diagnostic challenges. Our 2020 edition of this review showed thoracic (chest) imaging to be sensitive and moderately specific in the diagnosis of coronavirus disease
Cochrane COVID-19 Diagnostic Test Accuracy Group
core