Results 151 to 160 of about 443,911 (293)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The effects of mixture-induced local dependence on diagnostic classification [PDF]

, 2015
Diagnostic Classification Models (DCMs) have been extensively researched in recent psychometric literature for providing mastery skill profiles for diagnostic feedback (Henson, Templin, & Willse, 2009).
McCoy, Thomas P., NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Alzheimer’s Disease Detection Using Optimized Vision Transformer

Proceedings of the International Conference on Applied Innovations in IT
Alzheimer's disease (AD) is a complex, progressive neurodegenerative condition that affects millions of people worldwide, making early diagnosis critical for effective treatment and clinical management to improve quality of life.
Nasrallah Asem Al-Sultani, Alaa Taima Albu-Salih, Osama Majeed Hilal   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Remote online machine condition monitoring using advanced internet, wireless and mobile communication technologies [PDF]

, 2011
A conceptual model with wireless and mobile techniques is developed in this thesis for remote real-time condition monitoring, which is applied for monitoring, diagnosing, and controlling the working conditions of machines.
Peng, W
core  

Multitask Analysis Method for Tongue Image Based on Edge Computing

IEEE Access
In response to the application scenarios of modernized Traditional Chinese Medicine (TCM) diagnostic and treatment equipment moving towards the user end, an effort has been made to enhance the user-friendliness of TCM diagnostic and treatment devices ...
Tingting Song, Bin Liu, Fengen Yuan, Yunfeng Wang, Kang Yu, Hao Yang, Qiuyan Li   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A disease-centric vision-language foundation model for precision oncology in kidney cancer

Nature Communications
The non-invasive assessment of renal masses remains a critical challenge in urologic oncology, where diagnostic uncertainty frequently causes overtreatment.
Yuhui Tao, Zhongwei Zhao, Zilong Wang, Xufang Luo, Feng Chen, Kang Wang, Chuanfu Wu, Xue Zhang, Shaoting Zhang, Jiaxi Yao, Xingwei Jin, Xinyang Jiang, Yifan Yang, Dongsheng Li, Lili Qiu, Zhiqiang Shao, Jianming Guo, Nengwang Yu, Ying Xiong, Shuo Wang   +19 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source