Results 41 to 50 of about 241,567 (259)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Timely diagnostics of hydraulic equipment in metallurgical production

Литьë и металлургия, 2021
Precision control of hydraulic equipment is a distinctive feature of modern hydraulic systems. With the help of special diagnostic devices, it is possible to reliably and simply monitor the operation of hydraulic equipment. Diagnostic methods can be very
E. V. Gapeenko
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

How and why do Australians obtain blood pressure devices for use at home? A mixed-methods study revealing health literacy responsive ways to support this self-management behaviour

Health Literacy and Communication Open
Background Adequate health literacy is integral to support self-management behaviours, including home blood pressure (BP) monitoring, which is recommended for hypertension management.
Eleanor Clapham, Samuel Carmichael, Kaylee Slater, Aletta E. Schutte, John Stevens, Mark R. Nelson, Markus Schlaich, Rachel E. Climie, Ross T. Tsuyuki, George Stergiou, Norm RC Campbell, Dean S. Picone, Niamh Chapman   +12 more
doaj   +1 more source

Availability of technology for managing cancer patients in the Southeast European (SEE) region

Clinical and Translational Radiation Oncology, 2022
Background: The Southeast European (SEE) region of 10 countries and about 43 million people differs from Western Europe in that most SEE countries lack active cancer registries and have fewer diagnostic imaging devices and radiotherapy (RT) units.
Manjit Dosanjh, Mimoza Ristova, Vesna Gershan, Petya Georgieva, Marijana Balin Kovacevic, Ledio Bregu, Irma Coralic, Tamara Djurovic, Deyana Dosieva, Yiota Foka, Ana Fröbe, Konstantinos Hatziioannou, Costas J. Hourdakis, Yllka Kabashi, Dimitar Kalev, Ilir Kurtishi, Leandar Litov, Beqir Mezelxhiu, Svetlana Nestoroska Madjunarova, Gordana Nikolova, Damijan Skrk, Velda Smajlbegovic, Snezana Smichkoska, Igor Stojkovski, Primož Strojan, Zdravka Tecic, Dušanka Tešanović, Vladimir Todorovic, Zdravka Valerianova   +28 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

BASIC REQUIREMENTS AND PRINCIPLES OF CREATION ONBOARD DIAGNOSTIC SYSTEMS OF LOCOMOTIVES

Nauka ta progres transportu, 2014
Purpose. Justification of the basic principles of construction on-board diagnostic systems locomotive and choose from high-performance and reliable interface for the exchange of information on-board diagnostic systems. Methodology.
YE. B. Bodnar
doaj  

Concept Design of a High-Voltage Electrostatic Sanitizer to Prevent Spread of COVID-19 Coronavirus

Energies, 2021
In addition to public health measures, including social distancing, masking, cleaning, surface disinfection, etc., ventilation and air filtration can be a key component of a multi-pronged risk mitigation strategy against COVID-19 transmission indoors ...
Vahid Behjat, Afshin Rezaei-Zare, Issouf Fofana, Ali Naderian   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Comparing visual and automated urine dipstick analysis in a general practice population

Scandinavian Journal of Primary Health Care
Introduction Urinary symptoms constitute the primary reason for female patients to consult their general practitioner. The urinary dipstick test serves as a cornerstone for diagnosing urinary tract infections (UTIs), yet traditional visual interpretation
S. M. L. Cox, P. Hoitinga, G. J. Oudhuis, R. M. Hopstaken, P. H. M. Savelkoul, J. W. L. Cals, E. G. P. M. de Bont   +6 more
doaj   +1 more source