Results 141 to 150 of about 18,071 (216)

The effect of real‐news party cues

American Journal of Political Science, EarlyView.
Abstract News media routinely offer cues about the stances of party elites, but to what extent do these cues shape the policy opinions of the public? While numerous experiments find that partisans adopt the stances of their leaders, these findings may not generalize easily to the context of real news, which often contains richer policy information and ...
Rasmus Skytte
wiley   +1 more source

Evaluation of a Sensitive Visual Read Algorithm for Assessing 3R/4R Tau PET Images. [PDF]

J Nucl Med
Smith R, Garibotto V, Hägerström D, Jögi J, Ohlsson T, Strandberg O, Tonietto M, Janelidze S, Palmqvist S, Stomrud E, Klein G, Hansson O.   +11 more
europepmc   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Spatial patterns of tau accumulation across the Alzheimer's disease spectrum. [PDF]

Alzheimers Dement
Fonseca CS, Chao Y, La Joie R, Rabinovici GD, Jagust WJ, Harrison TM, Alzheimer's Disease Neuroimaging Initiative.   +6 more
europepmc   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Early Prediction of Neurological Outcome After Cardiac Arrest-Rationale and Design of the Prospective International Observational EARLY-NEURO, a STEPCARE Substudy. [PDF]

Acta Anaesthesiol Scand
Moseby-Knappe M, Westhall E, Admiraal M, Lang M, Levin H, Hästbacka J, Tiainen M, Skrifvars M, Lilja G, Jacobsen JC, Lagebrant A, Wise M, Reinikainen M, Young P, Saxena M, Schmidbauer S, Hammond N, Bass F, Ceric A, Kamp C, Sillassen C, Leithner C, Stammet P, Hilty MP, Wendel-Garcia PD, Royl G, Graf T, Thomas M, Sweet K, Bendel S, Tirkkonen J, Mengel A, Stefanou MI, Romundstad LG, Seidel P, Kåhlin J, Grip J, Heinonen J, Jadav RH, Nee J, Nowak D, Hänggi M, Undén J, Lybeck A, Düring J, Kenda M, Johnsson J, Nielsen N, Cronberg T.   +48 more
europepmc   +1 more source

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, EarlyView.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink, Chris L. Jaynes, L. Annick van Furth, Johannes Castelein, Nathan Ooms, Veerle A. Lantinga, Baran Ogurlu, Xiaopeng Zhou, Ulrike Dydak, Henri G. D. Leuvenink, Anna Krarup Keller, Ronald J. H. Borra, Cyril Moers   +12 more
wiley   +1 more source

Oseltamivir aziridines are potent influenza neuraminidase inhibitors and imaging agents. [PDF]

Proc Natl Acad Sci U S A
Vriends MBL, Moran E, Calvelo M, Hansen T, Pickles IB, Xin X, Biezeno M, Armstrong ZWB, Ferraz MJ, Li L, Lilley A, Harvey R, Filippov DV, Liao Q, Schröder SP, van der Marel GA, Artola M, Aerts JMFG, Blaza JN, Codée JDC, Rovira C, Overkleeft HS, Davies GJ.   +22 more
europepmc   +1 more source

Prenatal and childhood exposure to smoking and retinal nerve fibre layer thickness: A meta‐analysis of three independent birth cohorts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine retinal nerve fibre layer (RNFL) characteristics in relation to prenatal and postnatal smoking exposure in three independent birth cohorts: two Danish and one Australian cohort. Methods A combined meta‐analysis of peripapillary retinal nerve fibre thickness in the Copenhagen Prospective Studies on Asthma in Childhood 2000 ...
Linna Zhu, Inger Christine Munch, Samantha Sze‐Yee Lee, David A. Mackey, Tamo Sultan, Klaus Bønnelykke, Bo Chawes, Michael Larsen, Nicklas Brustad   +8 more
wiley   +1 more source

Vog: Using Volcanic Eruptions to Estimate the Health Costs of Particulates

The Economic Journal, EarlyView., 2018
The negative consequences of long‐term exposure to particulate pollution are well established but a number of studies find no effect of short‐term exposure on health outcomes. The high correlation of industrial pollutants complicates the estimation of the impact of individual pollutants on health.
Timothy J. Halliday, John Lynham, Áureo de Paula   +2 more
wiley   +1 more source