Results 211 to 220 of about 46,453 (252)

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

Cross-sectional study evaluating organizational climate, change commitment, and change efficacy for predicting family planning clinics' success in increasing HIV counseling and testing in Mombasa, Kenya. [PDF]

PLOS Glob Public Health
Kwendakwema CN, Eastment MC, Wanje G, Richardson BA, Mwaringa E, Sherr K, Mandaliya KN, Barnabas RV, Jaoko W, McClelland RS.   +9 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Cognitive reserve predicts baseline tau burden in the U.S. POINTER trial imaging cohort. [PDF]

Alzheimers Dement
Pavlik VN, Weber CJ, Masdeu JC, Baker LD, Yu MM, York M, Whitmer RA, Landau SM, Harrison TM, Holland TM, Lovato L.   +10 more
europepmc   +1 more source

Dating Apps and the Right to an Explanation

Journal of Applied Philosophy, EarlyView.
ABSTRACT This article argues that in countries where dating apps have become the primary means of meeting romantic partners and promise to help users find love, individuals should be entitled to access certain information about how their algorithms function. Specifically, we advocate for a legal right to an explanation that addresses the following, not
Bouke de Vries, Kristian González Barman   +1 more
wiley   +1 more source

Beyond the Critical Threshold: Elastic Fiber Remodeling and Fracture in the Pathogenesis of Pulmonary Emphysema. [PDF]

Int J Mol Sci
Cantor J.
europepmc   +1 more source

Longitudinal co‐development of mental and cardio‐metabolic health from childhood to young adulthood

Journal of Child Psychology and Psychiatry, EarlyView.
Background Depressive symptoms and cardio‐metabolic risk factors often co‐occur. However, our understanding of the potential mechanisms and temporal dynamics underlying their co‐development remains elusive. Methods This population‐based cohort study examined bidirectional longitudinal associations between depressive symptoms and cardio‐metabolic risk ...
Serena Defina, Charlotte A.M. Cecil, Janine F. Felix, Esther Walton, Henning Tiemeier   +4 more
wiley   +1 more source

Multivariate maternal effects across the internalizing–externalizing spectrum in childhood: results from the Norwegian mother, father, and child cohort study

Journal of Child Psychology and Psychiatry, EarlyView.
Background From a functionalist perspective, parenting behaviors have adaptive functions and are partly expressions of genetic variation. Maternal genes that have effects on children are often referred to as indirect maternal genetic effects. Indirect genetic effects provide a means for measuring the role of parenting without the need for specifying ...
Espen Moen Eilertsen, Nikolai Haahjem Eftedal, Rosa Cheesman, Ziada Ayorech, Joakim Coleman Ebeltoft, Hans Fredrik Sunde, Anneli Desiré Tandberg, Fartein Ask Torvik, Eivind Ystrom   +8 more
wiley   +1 more source

Hippocampal Subfield Volume in Relation to Cerebrospinal Fluid Amyloid-ß in Early Alzheimer's Disease: Diagnostic Utility of 7T MRI. [PDF]

Eur J Neurol
Adeyemi OF, Gowland P, Bowtell R, Mougin O, Hosseini AA.   +4 more
europepmc   +1 more source

Understanding memory dynamics in stroke patients: Learning and forgetting patterns based on verbal recall

Journal of Neuropsychology, EarlyView.
Abstract Memory deficits are common post stroke. Most episodic memory tests consist of a learning phase, immediate recall and a 30‐min delayed recall test. Recent research suggests a proportion of stroke patients exhibit accelerated long‐term forgetting after a longer delay.
Selma Lugtmeijer, Edward H. F. de Haan, Roy P. C. Kessels   +2 more
wiley   +1 more source