Results 31 to 40 of about 817,065 (297)

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Teasing apart trauma: neural oscillations differentiate individual cases of mild traumatic brain injury from post-traumatic stress disorder even when symptoms overlap

Translational Psychiatry, 2021
Post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) are highly prevalent and closely related disorders. Affected individuals often exhibit substantially overlapping symptomatology – a major challenge for differential diagnosis in
Jing Zhang, Zahra Emami, Kristina Safar, Patrick McCunn, J. Don Richardson, Shawn G. Rhind, Leodante da Costa, Rakesh Jetly, Benjamin T. Dunkley   +8 more
doaj   +1 more source

Imaging in vitreoretinal diagnostics

Indian Journal of Ophthalmology, 2013
Dear Friends, Greetings from the Editor's desk. I am privileged to introduce yet another monthly issue in this diamond jubilee year of our prestigious journal. This edition gives a fruitful insight into a wide range of subjects ranging from intraocular lenses to vein occlusion and retinal diagnostics.
openaire   +4 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Postoperative MR Defecography following Failed STARR Procedure for Obstructive Defecation Syndrome: A Three-Centre Experience

Gastroenterology Research and Practice, 2017
Aim. To describe the abnormalities at MR imaging and related complaints in patients with poor outcome after STARR procedure. Materials and Methods. The medical records of 21 symptomatic patients from centre 1, 31 patients from centre 2, and 63 patients ...
Vittorio Piloni, Marco Possanzini, Mattia Bergamasco, Gianluca Santi   +3 more
doaj   +1 more source

Validation of the educational effectiveness of a mobile learning app to improve knowledge about MR image quality optimisation and artefact reduction

Insights into Imaging, 2018
Aim The aim was to design an app-based eLearning tool to provide radiographers with information about the physical basis of MR artefacts and practical elimination or/and minimisation strategies to optimise image quality, and to evaluate the impact of a ...
Walaa Alsharif, Michaela Davis, Louise Rainford, Andrea Cradock, Allison McGee   +4 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

High resolution, 3-dimensional Ferumoxytol-enhanced cardiovascular magnetic resonance venography in central venous occlusion

Journal of Cardiovascular Magnetic Resonance, 2019
Background Although cardiovascular magnetic resonance venography (CMRV) is generally regarded as the technique of choice for imaging the central veins, conventional CMRV is not ideal.
Puja Shahrouki, John M. Moriarty, Sarah N. Khan, Biraj Bista, Stephen T. Kee, Brian G. DeRubertis, Takegawa Yoshida, Kim-Lien Nguyen, J. Paul Finn   +8 more
doaj   +1 more source

Tomographic score (RAD-Covid Score) to assess the clinical severity of the novel coronavirus infection

Brazilian Journal of Infectious Diseases, 2021
Objectives: The severity of pulmonary Covid-19 infection can be assessed by the pattern and extent of parenchymal involvement observed in computed tomography (CT), and it is important to standardize the analysis through objective, practical, and ...
Tatiana Figueiredo Guimarães Ribeiro, Ricardo Arroyo Rstom, Paula Nicole Vieira Pinto Barbosa, Maria Fernanda Arruda Almeida, Marina Martini Costa, Edivaldo Nery de Oliveira Filho, André Santos Barros, Talita Rombaldi Pereira, Silvio Fontana Velludo, Fabrício Próspero Machado   +9 more
doaj   +1 more source

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

FEBS Letters, EarlyView.
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio, Sofia Lövestam, Michael A. Metrick II, Thomas Löhr, Peifeng Xu, Nicholas C. T. Gallagher, Bernardino Ghetti, Byron Caughey, Sjors H. W. Scheres, Michele Vendruscolo   +9 more
wiley   +1 more source