In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
An Australian local diagnostic reference level for paediatric whole-body 18F-FDG PET/CT. [PDF]
Alkhybari EM +5 more
europepmc +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Diagnostic reference level curves for paediatric fluoroscopic imaging in the Netherlands. [PDF]
Croes GO +11 more
europepmc +1 more source
Assessment of Diagnostic Reference Level in Radiography of Neonatal Chest Anteroposterior Examination: A Hospital-based Study. [PDF]
Sharma J, Sarma J, Agarwal S.
europepmc +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Clinical Indication-Based Pediatric Diagnostic Reference Level Values for Abdominal Computed Tomography: A Descriptive Cross-Sectional Study. [PDF]
Pitso T, Sebelego IK, Muller H.
europepmc +1 more source
Establishment of institutional diagnostic reference level for computed tomography with automated dose-tracking software. [PDF]
Liang CR +5 more
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Detailed EFSUM recommendations on the scope of ultrasound assessment in patients with portal hypertension considering the diagnostic reference level. [PDF]
Smereczyński A, Kołaczyk K.
europepmc +1 more source

