Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The impact of the 2020 diagnostic reference level revision and the development of national regulations on occupational radiation protection in medical facilities in Japan. [PDF]
Tsujiguchi T +8 more
europepmc +1 more source
National diagnostic reference level initiative for computed tomography examinations in Kenya. [PDF]
Korir GK +4 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Establishing Diagnostic Reference Level for Adult Abdomen and Pelvis CT Scans: A Benchmarking Study across BMI Groups. [PDF]
M JM +5 more
europepmc +1 more source
Limitations of diagnostic reference level (DRL) and introduction of acceptable quality dose (AQD). [PDF]
Rehani MM.
europepmc +1 more source
Developing diagnostic reference levels in Japan
A nationwide network with participation from academic and professional societies,equipment suppliers, government authorities, and individual experts, called J-RIME,set the first national DRLs in June 2015 and updated them in July 2020. In this review, the contents of Japan DRLs and the process of their development were overviewed.
openaire
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Diagnostic reference level, achievable dose, and effective dose estimation in adult hybrid SPECT myocardial perfusion imaging in Institut Jantung Negara. [PDF]
Selvam HSS +6 more
europepmc +1 more source
Evidence of dose saving in routine CT practice using iterative reconstruction derived from a national diagnostic reference level survey. [PDF]
Thomas P +4 more
europepmc +1 more source

