Results 221 to 230 of about 14,286,320 (254)

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Sciatic Nerve Bifurcation and Anatomical Reference Points: Diagnostic and Clinical Implications. [PDF]

Diagnostics (Basel)
Aydin M, Savaşan C, Yilmaz M, Ozkubat E, Emmez G, Bayramoglu A, Esmer TS.   +6 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers, Part II: Follow-up Surveillance after Initial Treatment 2026. [PDF]

Endocrinol Metab (Seoul)
Lee EK, Kang SH, Koo BS, Kim M, Kim MJ, Kim BH, Kim JW, Na DG, Park S, Bang JI, Back K, Seo Y, Son YI, Song YS, Shin DY, Ahn JH, Ahn HY, Oh SW, Won HR, Yoo WS, Lee MK, Lee SW, Lee J, Lee JY, Lim DJ, Chung KW, Chong A, Jung JH, Cho SW, Cho YY, Hong CM, Park YJ, Korean Thyroid Association Guideline Committee on the Management of Thyroid Nodule and Cancer.   +32 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Diagnostic Accuracy of Leucocyte Esterase Reagent Strips for Spontaneous Bacterial Peritonitis in Cirrhosis With Ascites. [PDF]

Health Sci Rep
Mwinyi SA, Sindato EM, Muhimbura E, Kawishe GJ, Yahaya JJ.   +4 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Confidence-guided integration of otoscopy videos and tympanometry for middle ear disease diagnosis: A multi-center otoscopy study with external paired-cohort evaluation. [PDF]

PLoS One
Lu H, Langefeld CD, Zinnia A, Demir MF, Chavan S, Elmaraghy CA, Wilson M, Niazi MKK, Moberly AC, Gurcan MN.   +9 more
europepmc   +1 more source

Algorithmic Determinants of Performance Heterogeneity in Whole-Genome Sequencing-Based Prediction of Drug Resistance in <i>Mycobacterium tuberculosis</i>: A Systematic Review and Meta-Analysis. [PDF]

Microorganisms
Peng B, Zhou Y, Li X, Liu H, Zhao B, Hou P, Ou X, Zhao Y.   +7 more
europepmc   +1 more source

A MAGIBU-based model for pediatric and juvenile CNS tumors: an in-house epigenetic decision-support framework compared with online DNA methylation classifiers. [PDF]

Free Neuropathol
Mattei G, Giunti L, Scagnet M, Agushi R, Mussa F, Caporalini C, Sardi I, Civale VY, Magi A, Genitori L, Buccoliero AM.   +10 more
europepmc   +1 more source