Results 171 to 180 of about 597,510 (287)

DEVELOPMENT OF DIAGNOSTIC REFERENCE LEVELS (DRL) OF PATIENTS X-RAY EXPOSURE IN DIAGNOSTIC RADIOLOGY

, 2015
We introduce a system of Diagnostic Reference Levels (DRLs) for patients medical exposure for national health care practice implementation. DRLs are an effective way of the patient radiation protection through the optimization of the medical exposure ...
S. A. Kalnitsky, M. I. Balonov, I. G. Kamyshanskaja, A. V. Vodovatov   +3 more
core  

Local diagnostic reference levels for pediatric fluoroscopy in a Brazilian tertiary referral center: A weight‑based analysis. [PDF]

J Appl Clin Med Phys
Ribeiro CMC, Chaves TO, Decnop M, Gonçalves de Mendonça R, Varela MC, de Araujo CAV, Gomes Junior SC.   +6 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Establishment of Local Diagnostic Reference Levels for Adult CT Brain in Johannesburg, South Africa: A Retrospective Protocol Study. [PDF]

Diagnostics (Basel)
Seekoei KG, Phahlamohlaka NM, Du Plessis J, Mokhure SE.   +3 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Local Diagnostic Reference Levels for Common Nuclear Medicine Procedures for Pediatric in Dubai Health. [PDF]

Pediatr Rep
Dalah EZ, Mazrouei NKA, Ali ZAA.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

International survey in four European countries on diagnostic reference levels based on clinical indications in computed tomography. [PDF]

Insights Imaging
Schegerer AA, Jungnickel K, Walz M, Verius M, Singer J, Renger B, Oberhofer N, Müller C, Menz R, Madsack B, Fiebich M, Eßeling R, Borowski M, Bazrafshan B, Ammon J, Aberle C, Stamm G.   +16 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source