Results 91 to 100 of about 12,496 (206)

Angiographic Anatomy of Thoracic Organs

open access: yesMedEdPORTAL, 2011
Introduction This interactive tutorial serves as an introduction to normal vascular anatomy of thoracic organs for preclinical medical students.
Penprapa Klinkhachorn   +5 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Knowledge of the Methods Used by Dentists for Diagnosis and Treatment of Caries Lesions: A Pilot Study

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To investigate the methods used by dentists for diagnosis and treatment of dental caries lesions. Material and Methods: This cross-sectional study was developed by sending a validated questionnaire to dentists in the southeastern region of ...
Bárbara Stephanie Leal Dias   +2 more
doaj  

Restoration-Guided Implant Rehabilitation of the Complex Partial Edentulism: a Clinical Report [PDF]

open access: yeseJournal of Oral Maxillofacial Research, 2010
Background: The hard and soft tissue deficiency is a limiting factor for the prosthetic restoration and any surgical attempt to correct the anatomic foundation needs to be precisely executed for optimal results.
Nikitas Sykaras   +2 more
doaj  

Testing Cranial and Spinal Nerve Functional Integrity and Deficits (Out of Print)

open access: yesMedEdPORTAL, 2008
Introduction This virtual patient web-based resource was developed to evaluate diagnostic skills among first-year medical students regarding the cranial nerves as part of peripheral nervous system component of an objective structured clinical exam.
Frank Reilly   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Sedation for interventional gastrointestinal endoscopic procedures: are we overlooking the pain?

open access: yes, 2014
BACKGROUND: Although interventional gastrointestinal (GI) endoscopic procedures are known to cause greater pain and discomfort than diagnostic procedures, the efficacy of adequate pain control or the difference in pain and amount of analgesic required ...
김현주   +5 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy