Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Diagnostic test validation studies when there is a perfect reference standard
C. Heuer, Mark A. Stevenson
openalex +2 more sources
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Chronic Dacryocystitis – It’s Evaluation and Management by Various Investigative and Diagnostic Test
Pervez Ahemed Siddiqui
openalex +1 more source
Construction a Diagnostic Test in the Form of Two-tier Multiple Choice on Calculus Material [PDF]
Edy Nurfalah +4 more
openalex +1 more source
The Promise of Multicancer Early Detection. Comment on Pons-Belda et al. Can Circulating Tumor DNA Support a Successful Screening Test for Early Cancer Detection? The Grail Paradigm. Diagnostics 2021, 11, 2171 [PDF]
Eric A. Klein +2 more
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
A Test Strategy for Spurious Spatial Regression, Spatial Nonstationarity, and Spatial Cointegration [PDF]
A test strategy consisting of a twofold application of a Lagrange Multiplier test is suggested as a device to reveal spatial nonstationarity and spurious spatial regeression. It is further illustrated how the test strategy can be used as a diagnostic for
Jorgen Lauridsen, Reinhold Kosfeld
core

