Results 51 to 60 of about 16,288,597 (342)

Recommendations for reporting of systematic reviews and meta-analyses of diagnostic test accuracy: a systematic review

open access: yesSystematic Reviews, 2017
BackgroundThis study is to perform a systematic review of existing guidance on quality of reporting and methodology for systematic reviews of diagnostic test accuracy (DTA) in order to compile a list of potential items that might be included in a ...
Trevor A. McGrath   +7 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Convergence Behavior of Optimal Cut-Off Points Derived from Receiver Operating Characteristics Curve Analysis: A Simulation Study

open access: yesMathematics, 2022
The area under the receiver operating characteristics curve is a popular measure of the overall discriminatory power of a continuous variable used to indicate the presence of an outcome of interest, such as disease or disease progression.
Oke Gerke, Antonia Zapf
doaj   +1 more source

Modelling multiple thresholds in meta-analysis of diagnostic test accuracy studies

open access: yesBMC Medical Research Methodology, 2016
BackgroundIn meta-analyses of diagnostic test accuracy, routinely only one pair of sensitivity and specificity per study is used. However, for tests based on a biomarker or a questionnaire often more than one threshold and the corresponding values of ...
S. Steinhauser   +2 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests

open access: yesAutoimmunity, 2021
Objectives Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays.
Wynand Alkema   +10 more
doaj   +1 more source

Partial Verification Bias Correction Using Inverse Probability Bootstrap Sampling for Binary Diagnostic Tests

open access: yesDiagnostics, 2022
In medical care, it is important to evaluate any new diagnostic test in the form of diagnostic accuracy studies. These new tests are compared to gold standard tests, where the performance of binary diagnostic tests is usually measured by sensitivity (Sn)
Wan Nor Arifin, Umi Kalsom Yusof
doaj   +1 more source

Macimorelin as a Diagnostic Test for Adult GH Deficiency

open access: yesJournal of Clinical Endocrinology and Metabolism, 2018
Purpose The diagnosis of adult GH deficiency (AGHD) is challenging and often requires confirmation with a GH stimulation test (GHST). The insulin tolerance test (ITT) is considered the reference standard GHST but is labor intensive, can cause severe ...
Jose M. Garcia   +18 more
semanticscholar   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Diagnostics of cattle leucosis by using an biosensor based on surface plasmon resonance phenomenon

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2019
The virus of cattle enzootic leucosis leads to high losses in rural economy, implies forced slaughter of sick animals, loss of the breed, decrease in productivity, violation of reproduction processes in industrial breeding and livestock sector.
Z.S. Klestova
doaj   +1 more source

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