Results 51 to 60 of about 16,288,597 (342)
BackgroundThis study is to perform a systematic review of existing guidance on quality of reporting and methodology for systematic reviews of diagnostic test accuracy (DTA) in order to compile a list of potential items that might be included in a ...
Trevor A. McGrath+7 more
semanticscholar +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
The area under the receiver operating characteristics curve is a popular measure of the overall discriminatory power of a continuous variable used to indicate the presence of an outcome of interest, such as disease or disease progression.
Oke Gerke, Antonia Zapf
doaj +1 more source
Modelling multiple thresholds in meta-analysis of diagnostic test accuracy studies
BackgroundIn meta-analyses of diagnostic test accuracy, routinely only one pair of sensitivity and specificity per study is used. However, for tests based on a biomarker or a questionnaire often more than one threshold and the corresponding values of ...
S. Steinhauser+2 more
semanticscholar +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests
Objectives Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays.
Wynand Alkema+10 more
doaj +1 more source
In medical care, it is important to evaluate any new diagnostic test in the form of diagnostic accuracy studies. These new tests are compared to gold standard tests, where the performance of binary diagnostic tests is usually measured by sensitivity (Sn)
Wan Nor Arifin, Umi Kalsom Yusof
doaj +1 more source
Macimorelin as a Diagnostic Test for Adult GH Deficiency
Purpose The diagnosis of adult GH deficiency (AGHD) is challenging and often requires confirmation with a GH stimulation test (GHST). The insulin tolerance test (ITT) is considered the reference standard GHST but is labor intensive, can cause severe ...
Jose M. Garcia+18 more
semanticscholar +1 more source
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens+8 more
wiley +1 more source
Diagnostics of cattle leucosis by using an biosensor based on surface plasmon resonance phenomenon
The virus of cattle enzootic leucosis leads to high losses in rural economy, implies forced slaughter of sick animals, loss of the breed, decrease in productivity, violation of reproduction processes in industrial breeding and livestock sector.
Z.S. Klestova
doaj +1 more source