Results 81 to 90 of about 9,461,475 (306)

Development of a multicentre cohort study to understand the role of MRI and ultrasound in the diagnosis of acute haematogenous bone and joint infection in children (the PIC Bone study): a study protocol

Bone & Joint Open
Aims: Bone and joint infections (BJI) in children are rare but can be serious. Differentiating BJI from other conditions with similar symptoms is critical. Advanced imaging (ultrasound scans (USS) and MRI) is often required to confirm the diagnosis. The
Marie-Caroline Nogaro, Stuart Hartshorn, Mariea Brady, Amaka Offiah, Saul Faust, Gregory Firth, Jie Ma, Paula Dhiman, Joanna O'Mahoney, Loretta Davies, Catherine Spowart, Amy Moscrop, Bridget Young, Catrin Tudur-Smith, Gary Collins, Daniel C. Perry, Tim Theologis   +16 more
doaj   +1 more source

Just a Test

, 2018
An abstract abstract!An abstract ...
Test, Test
core  

Computational Modelling of malaria diagnostic test

, 2018
Early diagnosis of malaria is important for the prevention of malaria disease outbreak and providing an affected person with appropriate treatment early on.
Ryu, Kyungsuk, Fitzpatrick, Richard, Stefan, Melanie   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Biomarkers for diagnosis of Irritable Bowel Syndrome (IBS)

Bioingeniøren, 2016
Background: The diagnosis of Irritable Bowel Syndrome (IBS) is based on typical symptoms after exclusion of other disorders. There is a strong need for a biomarker that confirms the diagnosis. The paper reviews available biomarkers for IBS.
Per G. Farup
doaj  

Salivary diagnostic tests [PDF]

The Journal of the American Dental Association, 2012
The guest editor of this special supplement to JADA provides an overview of salivary diagnostic testing and introduces the articles presented in this supplement to The Journal of the American Dental Association.
openaire   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Difficulties and Correlation between Phenomenon and Reasoning Tier of Multiple-Choice Questions: A Survey Study

IRJE (Indonesian Research Journal in Education), 2019
Two-tier multiple-choice (2TMC) has been introduced as an instrument to analyze a conceptual understanding at tier 1 and reasoning to the answer at tier 2. Even there are many studies on using the instrument; there is still relatively little attention on
HILMAN QUDRATUDDARSI, RENUKA V SATHASIVAM, HUTKEMRI HUTKEMRI   +2 more
doaj  

Development and Validation of a High-Throughput Mass Spectrometry Based Urine Metabolomic Test for the Detection of Colonic Adenomatous Polyps

Metabolites, 2017
Background: Colorectal cancer is one of the leading causes of cancer deaths worldwide. The detection and removal of the precursors to colorectal cancer, adenomatous polyps, is the key for screening.
Lu Deng, David Chang, Rae R. Foshaug, Roman Eisner, Victor K. Tso, David S. Wishart, Richard N. Fedorak   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source