NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi+16 more
wiley +1 more source
Plasma Concentrations of Matrilysins (MMP-7, MMP-26) and Stromelysins (MMP-3, MMP-10) as Diagnostic Biomarkers in High-Grade Serous Ovarian Cancer Patients. [PDF]
Ewa G+7 more
europepmc +1 more source
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley +1 more source
Case Report: Practical approach to unmask unspecific adverse effects under lipid-lowering medication. [PDF]
Büttner T, Hartmann G, Coenen M.
europepmc +1 more source
Metagenomic Next-Generation Sequencing for the Diagnosis of Infectious Uveitis: A Comprehensive Systematic Review. [PDF]
Pardo I+13 more
europepmc +1 more source
A High-Sensitivity Troponin I Rapid Assay vs. a High-Sensitivity Troponin T Routine Assay in Acute Chest Pain Patients: A Prospective Monocentric Study. [PDF]
Han E+7 more
europepmc +1 more source
False alarm on a malaria "outbreak" linked to inconsistencies in malaria diagnostic supply: a call to strengthen supply chain management: Sierra Leone, May-July 2023. [PDF]
DeVita TN+11 more
europepmc +1 more source
Could it be <i>Brucella melitensis</i>? Recognizing and managing a rare pathogen in periprosthetic infections. [PDF]
Abul MS+3 more
europepmc +1 more source