Results 131 to 140 of about 2,023,088 (340)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Gathering and managing complementary diagnostic tests [PDF]

open access: yes, 2010
Personal health information is constituted in its greatest part by complementary diagnostic tests which are an important medical aid. This information is generated dispersedly because the patient seeks medical care in many different places over his ...
Costa, Carlos Manuel Azevedo   +3 more
core  

The importance of external quality assessment data in evaluating SARS-CoV-2 virus genome detection assays

open access: yesThe Lancet Microbe, 2022
Christoph Buchta   +2 more
doaj  

Appropriateness of diagnostic tests

open access: yesClinical Management Issues, 2012
Francesco Cipollini
doaj   +1 more source

The Anoxemia Test as a Diagnostic Tool [PDF]

open access: bronze, 1958
Ralph B. Winston, D Dutrey
openalex   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Economic consequences of near-patient test results - the case of tests for the Helicobacter Pylori bacterium in dyspepsia [PDF]

open access: yes
Diagnostic tests and in particular laboratory tests are often important in diagnostic work-up and monitoring of patients. Therefore the economic consequences of medical actions based on test results may amount to a substantial proportion of health ...
Fauli, Siri, Thue, Geir
core  

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