Results 131 to 140 of about 17,584,259 (393)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

On the role of depletive tests. a review analysis [PDF]

, 2016
An overview of the diagnostic role of depletion tests for staging Meniere’s disease, especially in the first phase of the disease, is reported.
Barbara, M, Covelli, E, Marrone, V, Monini, S, Tarentini, S   +4 more
core  

Diagnostic test pepsinogen I and combination with tumor marker CEA in gastric cancer [PDF]

, 2018
J Sembiring, K Sarumpaet, Ratna Akbari Ganie   +2 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Early Identification of Sepsis-Induced Acute Kidney Injury by Using Monocyte Distribution Width, Red-Blood-Cell Distribution, and Neutrophil-to-Lymphocyte Ratio

Diagnostics
Sepsis-induced acute kidney injury (AKI) is a common complication in patients with severe illness and leads to increased risks of mortality and chronic kidney disease.
Yi-Hsiang Pan, Hung-Wei Tsai, Hui-An Lin, Ching-Yi Chen, Chun-Chieh Chao, Sheng-Feng Lin, Sen-Kuang Hou   +6 more
doaj   +1 more source

Mental Disorder Diagnostic System Based on Logical-Combinatorial Methods of Pattern Recognition [PDF]

Computer Science Journal of Moldova, 2013
The authors describe mental disorder diagnostic system based on logical-combinatorial methods of pattern recognition called as the intelligent system DIAPROD-LOG. The system is designed for diagnostics and prevention of depression.
Anna Yankovskaya, Sergei Kitler
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Oral Contraceptives and Thyroid Results: Navigating the Complex Interactions and Clinical Implications

Journal of Education, Health and Sport
This review explores the complex interactions between birth control pills and thyroid function, emphasizing the potential for misinterpreted thyroid test results and the risks associated with inappropriate treatment. Birth control pills, widely used for
Maria Morawska, Klaudia Kożuchowska, Dawid Pilarz, Marcelina Szewczyk, Anna Wolff, Julia Ufnal, Dominika Lewandowska, Dominika Rosińska-Lewandoska , Helena Udziela-Gil, Kinga Jarosz   +9 more
doaj   +1 more source

Evaluation of feline leukemia virus diagnostic tests available for in-office use by veterinarians [PDF]

, 1991
Larry J. Swango
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source