Results 131 to 140 of about 1,151,345 (268)

Understanding diagnostic tests. Part 1.

Jornal Brasileiro de Pneumologia
Juliana Carvalho Ferreira, Cecilia Maria Patino   +1 more
doaj   +1 more source

Associations Between Preoperative Diagnostic Tests and Surgical Recommendation for Carpal Tunnel Syndrome. [PDF]

J Hand Surg Glob Online
Iglesias B, Hua K, Weinberg J, Gonzalez C, Dan X, Ma Y, Fowler J.   +6 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Diagnostic tests for autism spectrum disorder (ASD) in preschool children. [PDF]

Cochrane Database Syst Rev
Brignell A, Chan K, Chellew T, Maddumahewa CV, Wong N, Hooft L, Alshawsh M, Williams K.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Propuesta de esquemas de tratamiento antituberculosis basados en la susceptibilidad A isoniacida y rifampicina

Revista Peruana de Medicina Experimental y Salud Pública
Objetivo. Elaborar esquemas de tratamiento para tuberculosis de acuerdo con sus perfiles de susceptibilidad a isoniacida (H) y rifampicina (R). Materiales y métodos. Un total de 12 311 aislamientos de M.
Alberto Mendoza-Ticona, David AJ Moore, Valentina Alarcón, Frine Samalvides, Carlos Seas   +4 more
doaj  

Impact of liver cirrhosis etiology on results of diagnostic tests for minimal hepatic encephalopathy. [PDF]

Sci Rep
Egge JFM, Ehrenbauer AF, Gabriel MM, Tiede A, Al-Ayoubi J, Witt J, Mauz JB, Kabelitz MA, Wagner LS, Wedemeyer H, Grosshennig A, Grosse GM, Maasoumy B, Weissenborn K.   +13 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Impact of <i>in vitro</i> diagnostic tests in health, society and economy in Portugal. [PDF]

Front Public Health
Rodrigues P, Mota S, Amaral C, Garganta B, Catalão C, de Almeida L, Teixeira I, Costa P, Dias P.   +8 more
europepmc   +1 more source