Results 201 to 210 of about 17,010,700 (403)

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

TESTS OF THE DIAGNOSTIC-CYCLE ROUTINE IN THE INTERPRETATION OF LAYER-CLOUD EVOLUTIONS¹

, 1966
Roland E. Nagle, James R. Clark, Manfred M. Holl   +2 more
openalex   +1 more source

Reliability of HIV rapid diagnostic tests for self-testing compared with testing by health-care workers: a systematic review and meta-analysis

The Lancet HIV, 2018
Carmen Figueroa, C. Johnson, N. Ford, A. Sands, S. Dalal, Robyn Meurant, Irena Prat, K. Hatzold, W. Urassa, R. Baggaley   +9 more
semanticscholar   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Could Low-Value Diagnostic Tests be Compounding Access Block? A Single-Site, Cross-Sectional Study. [PDF]

Emerg Med Australas
Walker H, West C, Lawton L, Emeto TI, Gangathimmaiah V.   +4 more
europepmc   +1 more source

Diagnostic Effectiveness of Biochemical Liver-Function Tests, as Evaluated by Discriminant Function Analysis [PDF]

, 1977
Paul Phillip Sher
openalex   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Health economic evaluations of diagnostic tests for tuberculosis: a narrative review. [PDF]

Health Econ Rev
Arpa C, Abd El Wahed A, Aydin S, Ghosh P, Mondal D, Nakiyingi L, Okuni JB, Schneitler S, Weidmann M, Siegel M.   +9 more
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Diagnostic tests performance indices: an overview. [PDF]

Biochem Med (Zagreb)
Habibzadeh F.
europepmc   +1 more source