Results 201 to 210 of about 5,259,808 (319)

Patient perspectives on diagnostic uncertainty and novel diagnostic tests in neuro-oncology. [PDF]

Neurooncol Pract
Ruijters VJ, Bauer MM, Tolboom N, Seute T, Visser LNC, Snijders TJ.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Low practical knowledge but high willingness to use malaria rapid diagnostic tests among healthcare workers in the Republic of Congo. [PDF]

BMC Public Health
Baina MT, Mouanga AM, Vouvoungui C, Diafouka-Kietela S, Ngambou Nguissaliki M, Diallo N, Ntoumi F.   +6 more
europepmc   +1 more source

Choice of Diagnostic Tests

Journal of the Royal College of Physicians of London, 1975
openaire   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Diagnostic tests for autism spectrum disorder (ASD) in preschool children. [PDF]

Cochrane Database Syst Rev
Brignell A, Chan K, Chellew T, Maddumahewa CV, Wong N, Hooft L, Alshawsh M, Williams K.   +7 more
europepmc   +1 more source

Associations Between Preoperative Diagnostic Tests and Surgical Recommendation for Carpal Tunnel Syndrome. [PDF]

J Hand Surg Glob Online
Iglesias B, Hua K, Weinberg J, Gonzalez C, Dan X, Ma Y, Fowler J.   +6 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Diagnostic tests for corneal diseases

Indian Journal of Ophthalmology, 1994
Sachdev Mahipal, Honavar Santosh, Thakar Meenakshi   +2 more
doaj  

Sensitivity of Tuberculosis Infection Diagnostic Tests Among Different Populations: A Systematic Review and Meta-analysis. [PDF]

Open Forum Infect Dis
Rana N, Noseworthy R, Jabbour E, Palmert T, Salah M, Robayo SD, Nafade V, Santos VS, Campbell JR.   +8 more
europepmc   +1 more source