Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Beyond diagnostic test performance: two content-validated questionnaires assessing patient and clinician satisfaction with diagnostic tests. [PDF]
Chang SN +10 more
europepmc +1 more source
Non-invasive diagnostic tests for Helicobacter pylori infection.
L. Best +7 more
semanticscholar +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Awareness and attitudes of pregnant women about prenatal screening and diagnostic tests from Türkiye. [PDF]
Kaymak D +7 more
europepmc +1 more source
Accuracy of diagnostic tests for prosthetic joint infection: a systematic review
Sufian S. Ahmad +5 more
semanticscholar +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Diagnostic tests for corneal diseases
Sachdev Mahipal +2 more
doaj
Impact of FilmArray Gastrointestinal Panel Compared to Standard-of-Care Diagnostic Tests in Clinical Practice of Acute Gastroenteritis in an HIV Reference Center with Limited Resources. [PDF]
Henn GAL +5 more
europepmc +1 more source

