Results 41 to 50 of about 17,010,700 (403)

Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis

open access: yesBritish medical journal, 2020
Objective To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (covid-19). Design Systematic review and meta-analysis. Data sources Medline, bioRxiv, and medRxiv from 1 January to 30 April 2020, using subject headings or
Mayara Lisboa Bastos   +12 more
semanticscholar   +1 more source

Common pitfalls in statistical analysis: Understanding the properties of diagnostic tests – Part 1

open access: yesPerspectives in Clinical Research, 2018
In this article in our series on common pitfalls in statistical analysis, we look at some of the attributes of diagnostic tests (i.e., tests which are used to determine whether an individual does or does not have disease). The next article in this series
P. Ranganathan, Rakesh Aggarwal
semanticscholar   +1 more source

Automated Particle Identification through Regression Analysis of Size, Shape and Colour [PDF]

open access: yes, 2016
Rapid point of care diagnostic tests and tests to provide therapeutic information are now available for a range of specific conditions from the measurement of blood glucose levels for diabetes to card agglutination tests for parasitic infections.
Cooper, J.M.   +2 more
core   +1 more source

Diagnosis of childhood tuberculosis and host RNA expression in Africa [PDF]

open access: yes, 2014
Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with ...
Amelia C. Crampin   +26 more
core   +4 more sources

PD-L1 diagnostic tests: a systematic literature review of scoring algorithms and test-validation metrics

open access: yesDiagnostic Pathology, 2018
BackgroundThe programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses.
M. Udall   +6 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Molecular Diagnostic Tests for Microsporidia

open access: yesInterdisciplinary Perspectives on Infectious Diseases, 2009
The Microsporidia are a ubiquitous group of eukaryotic obligate intracellular parasites which were recognized over 100 years ago with the description of Nosema bombycis, a parasite of silkworms.
Kaya Ghosh, Louis M. Weiss
doaj   +1 more source

Diagnostic error reduction in the United States and Italy through the intervention of diagnostic management teams [PDF]

open access: yes, 2018
A major challenge to most countries is the growing cost of healthcare. The cost of laboratory testing is approximately 3% of the total clinical costs.
Adriana Berumen Velazquez   +2 more
core  

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