Results 51 to 60 of about 2,023,088 (340)

Diagnostic tests for chancroid [PDF]

Sexually Transmitted Infections, 2000
The identification of the causative agent of chancroid, Haemophilus ducreyi , was first reported in 1889 by August Ducrey, as a short streptobacillary rod with rounded ends, following experiments in which he autoinoculated patients' forearms with pus from their genital ulcers.1 Bezancon et al subsequently inoculated the forearms of human volunteers ...
openaire   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Rodent Diagnostic Testing

Journal of Exotic Pet Medicine, 2008
Clinical medicine is an important part of scientific medicine that is all too often neglected when treating rodents and small mammal pets. As with more traditional pets, a progressive diagnostic regimen should include a thorough history, clinical signs, physical examination, and laboratory findings.
openaire   +2 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

How does study quality affect the results of a diagnostic meta-analysis? [PDF]

, 2005
Background: The use of systematic literature review to inform evidence based practice in diagnostics is rapidly expanding. Although the primary diagnostic literature is extensive, studies are often of low methodological quality or poorly reported.
A Biggi, A Fretzayas, A Gervaix, A Haberlik, A Hitzel, A Hitzel, A Hoberman, A Hoberman, A Hoberman, A Piepsz, AG Weinberg, AL Valentini, AM Rickwood, AM Rodriguez Caballero, AR Bergius, AS Aronson, AS Detsky, B Bagni, B Boudailliez, B Bulloch, B Jakobsson, B Lejeune, B Mucci, B Schersten, BA Jantausch, BP Barry, BS Elison, C De Sadeleer, C Godard, C Radmayr, C Villanustre Ordonez, CE Armengol, CE Armengol, CE Johnson, CE Johnson, CM Kunin, CV Pryles, D Baronciani, D Benador, D Landau, D Landau, D Lindsell, D Moher, D Morin, D Siamplis, D Vickers, DA Revicki, DC Hanbury, DG Altman, DL Sackett, DS Lin, DS Lin, E Cid, E Stokland, E Stokland, E Stokland, E Stokland, EC Vamvakas, ED Evans, ES Traisman, F Castello Girona, F Guermazi, FE Pickworth, FJ Marsik, FY Anad, G Alzen, G Bower, G Capa Kaya, G Krzemien, G La Cava, G Piaggio, G Rich, G Schreiter, G Vangone, GA McLorie, GJ Lonergan, GN Sfakianakis, GR Barnett, GR Lockhart, GS Liptak, GW LeQuesne, H Braude, H Saxena, H Tahirovic, HA Cohen, HC Scherz, HJ Mentzel, I Gordon, IG Verber, IJ Ramage, J Benito Fernandez, J Benito Fernandez, J Labbe, J Matthai, J Misselwitz, J Parmington, J Pylkkanen, J Pylkkanen, J Rodriguez Cervilla, J Todd, J Wiggelinkhuizen, JA Knottnerus, JA Lohr, JC Leonidas, JD Baum, JD Hardy, JF Redman, JG Lijmer, JG Mongeau, JJ Deeks, JL Fleiss, JM Littlewood, JM Smellie, JN Dacher, Jos Kleijnen, JR MacKenzie, K Everaert, K Mage, K Schneider, KN Shaw, KN Shaw, KOR Flegel, L Irwig, L Kohler, L Von Rohden, LE Moses, LS Palmer, M Demi, M el Hajjar, M Farrell, M Giraldez, M Hellstrom, M Hiraoka, M Ilyas, M Marret, M Nakamura, M Rehling, M Salih, M Uhl, M Verboven, MA Rossleigh, MA Santos, Marie E Westwood, MC Reid, MD Muro, MH Gorelick, MN Woodward, MP Andrich, MP Lavocat, MR Ditchfield, MV Merrick, N Buyan, N Dominguez Navarrete, N Sharief, OJ Muensterer, P Juni, P Juni, P Whitear, P Whiting, P Whiting, P Whiting, PC Boreland, PD Holland, Penny F Whiting, PJ Hedman, PM Bossuyt, PM Cavanagh, PMM Bossuyt, PS Dayan, PS Dayan, R Bachur, R Drachman, R Kenda, R Lagos Zuccone, R Manson, R Oostenbrink, R Wujanto, RB Kenda, RD Craver, RD Wammanda, RE Morton, RH Farnsworth, RL McEwing, RM Kessler, RS Fennell, S Arslan, S Bykov, S Dosa, S Feasey, S Hellerstein, S Jequier, S Jequier, S Li Volti, S Mahant, S Montplaisir, S Struthers, SB Sheps, SEM Clarke, SM Tan, T Ahmad, T Berrocal, T Berrocal Frutos, T Dura Trave, U Alon, V Benigno, V Smolkin, V Sreenarasimhaiah, VN Purwar, WH Foresman, Y Waisman, YL Chan, ZE Bircan   +211 more
core   +3 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Comparative efficacy of conventional diagnostic methods and evaluation of polymerase chain reaction for the diagnosis of bovine brucellosis [PDF]

Veterinary World, 2010
The comparative efficacy of Rose Bengal Plate Test (RBPT) and Milk Ring test (MRT) was calculated in terms of sensitivity and specificity for the diagnosis of bovine brucellosis in cows (Group A) and buffaloes (Group B) from Lahore and Okara districts of
Raheela Akhtar, Prof. Zafar Iqbal Chaudhry, Prof. A. R Shakoori, Mansoor ud Din Ahmad and Asim Aslam   +3 more
doaj  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Is scale-up worth it? Challenges in economic analysis of diagnostic tests for tuberculosis. [PDF]

, 2011
David Dowdy and colleagues discuss the complexities of costing new TB diagnostic tests, including GeneXpert, and argue that flexible analytic tools are needed for decision-makers to adapt large-sample cost-effectiveness data to local ...
Cattamanchi, Adithya, Dowdy, David W, Pai, Madhukar, Steingart, Karen R   +3 more
core   +4 more sources