Results 71 to 80 of about 2,023,088 (340)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

A survey of statistics in three UK general practice journal [PDF]

open access: yes, 2004
Background Many medical specialities have reviewed the statistical content of their journals. To our knowledge this has not been done in general practice.
A Donner   +33 more
core   +3 more sources

An evaluation of a referral management and triage system for oral surgery referrals from primary care dentists: a mixed-methods study

open access: yesHealth Services and Delivery Research, 2018
Background: Oral surgery referrals from dentists are rising and putting increased pressure on finite hospital resources. It has been suggested that primary care specialist services can provide care for selected patients at reduced costs and similar ...
Joanna Goldthorpe   +7 more
doaj   +1 more source

Diagnostic Accuracy of Ultrasonography and Radiography in Detection of Pulmonary Contusion; a Systematic Review and Meta-Analysis

open access: yesArchives of Academic Emergency Medicine, 2018
Introduction: Ultrasonography is currently being used as one of the diagnostic modalities in various medical emergencies for screening of trauma patients.
Mostafa Hosseini   +7 more
doaj   +1 more source

Development of Diagnostic Tests for Detection of SARS-CoV-2

open access: yesDiagnostics, 2020
One of the most effective ways to prevent the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is to develop accurate and rapid diagnostic tests. There are a number of molecular, serological, and imaging methods that are used to
Ngan N. T. Nguyen   +3 more
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Local Sensitivity and Diagnostic Tests [PDF]

open access: yes
In this paper we confront sensitivity analysis with diagnostic testing.Every model is misspecified, but a model is useful if the parameters of interest (the focus) are not sensitive to small perturbations in the underlying assumptions. The study of the e
Magnus, J.R., Vasnev, A.L.
core   +1 more source

Diagnosis of childhood tuberculosis and host RNA expression in Africa [PDF]

open access: yes, 2014
Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with ...
Amelia C. Crampin   +26 more
core   +3 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Prokaryotic Expression of the Influenza A (H5N1) Neuraminidase

open access: yesJournal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Highly Pathogenic Influenza A(H5N1) viruses cause vast economic losses throughout the world. They may circulate in animals and be able to spread from human to human.
Zahra Latif   +3 more
doaj  

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