Results 81 to 90 of about 2,023,088 (340)

Diagnostics: A testing journey [PDF]

open access: yesNature, 2011
Results ready in minutes and more efficacious drugs will help find and treat the hundreds of millions of carriers.
openaire   +3 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Mental Disorder Diagnostic System Based on Logical-Combinatorial Methods of Pattern Recognition [PDF]

open access: yesComputer Science Journal of Moldova, 2013
The authors describe mental disorder diagnostic system based on logical-combinatorial methods of pattern recognition called as the intelligent system DIAPROD-LOG. The system is designed for diagnostics and prevention of depression.
Anna Yankovskaya, Sergei Kitler
doaj  

The tip of the iceberg: finding patients with heart failure with preserved ejection fraction in primary care. An observational study

open access: yesBJGP Open, 2018
Background: Heart failure with preserved ejection fraction (HFpEF) is under-identified in primary care. Aim: The aim of this study was to determine what information is available in patients’ primary care practice records that would identify patients with
Christi Deaton   +3 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Improving Accuracy of Influenza-Associated Hospitalization Rate Estimates

open access: yesEmerging Infectious Diseases, 2015
Diagnostic test sensitivity affects rate estimates for laboratory-confirmed influenza–associated hospitalizations. We used data from FluSurv-NET, a national population-based surveillance system for laboratory-confirmed influenza hospitalizations, to ...
Alexander J. Millman   +17 more
doaj   +1 more source

EVALUATION OF HELICOBACTER PYLORI IN PATIENTS INVOLVED TO CHRONIC DYSPEPSIA

open access: yesПаёми Сино, 2020
Objective: To determine the frequency of Helicobacter pylori (HP) in patients with chronic dyspepsia referred to private laboratories in Mazar-i-Sharif city in 2019.
H. PARSA, G.H. MUSHTARI
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

How Diagnostic Tests Affect Prevention: a Cost-Benefit Analysis [PDF]

open access: yes
The purpose of this paper is to offers insight for evaluating research and development in diagnostic tests. We show that a rational policy maker perfectly informed about health risks may choose to reduce investment in prevention when efficient diagnostic
Christian Gollier   +2 more
core  

On the role of depletive tests. a review analysis [PDF]

open access: yes, 2016
An overview of the diagnostic role of depletion tests for staging Meniere’s disease, especially in the first phase of the disease, is reported.
Barbara, M   +4 more
core  

Home - About - Disclaimer - Privacy