Results 231 to 240 of about 1,002,484 (308)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Closing gaps through innovation in the tuberculosis pathology value chain. [PDF]

J Clin Tuberc Other Mycobact Dis
David A, Scott L, da Silva P, Stevens W.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Correction: Bednarek et al. Serum Osteoprotegerin Level Is Not a Localizing Biomarker of Atherosclerosis Affected by Kidney Function. <i>Diagnostics</i> 2026, <i>16</i>, 786. [PDF]

Diagnostics (Basel)
Bednarek AM, Owczarek AJ, Dziadosz D, Olszanecka-Glinianowicz M, Chudek JT.   +4 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

P271: Two copies, one condition? Understanding APOE allele state in over 14,000 symptomatic patients

Genetics in Medicine Open
Zoe Powis, Khalida Liaquat, Raveen Basran, Zhenyuan Wang   +3 more
doaj   +1 more source

Femoral Osteochondritis Dissecans and Tibial Osteochondral Defect in an Adult Revealed by Bone SPECT/CT. [PDF]

Diagnostics (Basel)
Chuang TL, Liu KC, Lin CW, Huang CH, Wang YF.   +4 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

High-Risk Thymoma Hidden Within a Cystic Thymic Lesion: A Diagnostic Clue from Diffusion-Weighted MRI. [PDF]

Diagnostics (Basel)
Bae K, An HJ, Jeon KN.
europepmc   +1 more source