Results 151 to 160 of about 5,371,543 (306)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

La loi avance, les phytos reculent

open access: yes, 2019
Après l’interdiction des pesticides chimiques dans les espaces gérés par l’État et les collectivités, c’est désormais au tour des particuliers d’y renoncer.
Revue d'urbanisme Diagonal
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Pressupost anual 2011 del Consorci del Campus Interuniversitari Diagonal-Besòs

open access: yes, 2010
Aprovació inicial pel Gerent del Consorci el 14-10-2010Aprovació definitiva pel Consell General del Consorci de 03-12-2010Informe econòmic-financer i annex del pressupost del Consorci del Campus Interuniversitari Diagonal-Besòs per a l'exercici ...
Consorci del Campus Interuniversitari Diagonal-Besòs
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Avec l’agence INterland, une boussole des valeurs pour mieux aménager les sols vivants

open access: yes
Imaginé et porté par la DGALN, l’Atelier des territoires accompagne les collectivités dans la construction d’un projet d’aménagement ou de renouvellement urbain.
Revue d'urbanisme Diagonal
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

ON THE ALMOST CONTINUITY OF THE DIAGONAL OF FUNCTIONS [PDF]

open access: yesReal Analysis Exchange, 1997
null Doliwa, null Pawlak
openaire   +1 more source

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