Results 81 to 90 of about 2,325,912 (296)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Strength Performance of an Eccentric Jacket Substructure

Journal of Marine Science and Engineering, 2019
An eccentric jacket substructure is comprised of circular hollow section tubular joints with complete overlap of braces. The joint is formed with the lap brace overlapping the diagonal through the brace joining the chord face.
Xiaoshuang Han, Anlong Chen, Bo Zhou, Guiyong Zhang, Wie Min Gho   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Stability Analysis of “321” Prefabricated Highway Steel Truss Bridge

Buildings
The “321” prefabricated highway steel truss bridge is widely used for highway rescue, disaster relief, and emergency traffic. This paper uses a 33 m double-row monolayer “321” prefabricated highway steel truss bridge to analyze its mechanical properties ...
Haifang He, Yulong Zhou, Shoushan Cheng, Ning An, Hongyi Liu, Zhixuan Fei   +5 more
doaj   +1 more source

Billa Kalina [cartographic material] /

, 1948
Topographic map of Billa Kalina, South Australia. Relief shown by spot heights.; On verso: Mis.13080.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. National Mapping Section.
core   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Central diagonal sections of Gaussian cubes

The investigation of the volume, surface area, and other geometric properties of sections of convex bodies, and in particular cubes, has a long history and a rich literature. However, much less is known when the cube has a volume distribution that is different from the Lebesgue measure; for example, a Gaussian density.
Fodor, Ferenc, Merino, Bernardo González   +1 more
openaire   +2 more sources

RESEARCH ON DAMAGE DEGREE ASSESSMENT METHOD OF ROLLING BEARING INNER RING BASED ON DIAGONAL SLICE SPECTRUM AND GREY RELATIONAL GRADE

Jixie qiangdu, 2019
Aiming at the problem that the fault information of rolling bearing was weak and susceptible to noise, which was difficult to judge the damage degree of bearing failure, a new method was proposed.
JIANG ZhangLei, WU YaPeng, WANG JiFang, XU XiaoLi   +3 more
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source