Results 121 to 130 of about 3,965,801 (321)
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
HOW VISIO 2003 CAN INFLUENCE INFORMATION TECHNOLOGY–CREATING UML MODELS [PDF]
Developing an overall architecture and design before you begin to write code helps you produce asoftware system that meets requirements and is easier to develop and maintain in the long run.
Adrian LUPASC
doaj
Mathematical model of the diagram of the Fe-Si-B composition system
A diagram of the phase composition of the Fe – Si – B system is constructed in the form of elementary triangles of coexisting phases and its mathematical model was created. Its isothermal sections are given in the temperature range of 300 - 2 000 K.
A. A. Akberdin +3 more
doaj
On the construction of direct daylight factor diagrams with allowance for transmission losses through glass [PDF]
Allyson Stevenson
openalex +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
The ultracentrifugal protein sedimentation diagram of normal human, cow and horse serum [PDF]
A. S. McFarlane
openalex +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
The Plan as Eidos: Bramante’s Half-Drawing and Durand’s Marche
By confronting Bramante’s plan for St Peter Basilica (1503) with Durand’s “Method of Composition” - summarized in his Marche plate (1802) - a modern conceptualisation of the plan unfolds which can be explained through the philosophical notion of eidos ...
Alejandra Celedón
doaj

