Results 171 to 180 of about 4,142,479 (322)

A Vector Diagram [PDF]

Science, 1907
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Deciphering the toxicological mechanism of airway allergic diseases caused by dioctyl terephthalate: a composite study. [PDF]

Front Toxicol
Zhang ZQ, Bao YW, Wang H, Li JY, Wang H, Yang X, Chen Q, Wu J, Zhu XH.   +8 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Surgical algorithms for ankylosing spondylitis-related pseudarthrosis : adapting to radiological and clinical variations. [PDF]

Bone Jt Open
Qiao M, Qian BP, Wang K, Song CY, Lu JS, Qiu Y.   +5 more
europepmc   +1 more source

Diagrams

, 2018
Tijdens het eindsymposium van Diagrams werden de resultaten vanuit Hanzehogeschool gepresenteerd.
openaire  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Design and testing of frequency-doubling microstrip antenna sensor for wireless monitoring of high temperatures. [PDF]

Microsyst Nanoeng
Dong H, Guo L, Zhen C, Dong T, Fu H, Tian X, Liang S, Feng R, Tan Q.   +8 more
europepmc   +1 more source

Analisa Penjadwalan Proyek Rentang Headworks And Cipelang Main Canal Upgrading Works Rentang Irrigation Modernization Project (RIMP) Dengan Metode Diagram Pareto Kecamatan Jatitujuh Kabupaten Majalengka

, 2023
Agus Hidayat, Lia Lailla Nurjamilah, Erni Sari Lombun Taruan   +2 more
openalex   +2 more sources