Results 31 to 40 of about 95,054 (301)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diagnosis Quest

open access: yesMedEdPORTAL, 2010
Introduction Diagnosis Quest is a software program that simulates an ambulatory patient encounter. A patient problem is the departure point for assessing a student's skills in patient evaluation and diagnosis formulation through an open-ended learner ...
Richard Morehead, Robert Fons
doaj   +1 more source

Enhancing the Ultrasonic Welding of Wood Using 3D Printed Lignin Energy Directors

open access: yesAdvanced Science, EarlyView.
Sustainable manufacturing for lightweight structures using ecofriendly materials will be key to reducing material consumption and lowering carbon footprints. Here, an approach is presented to weld wood using ultrasonic vibrations with material at the joint interface to direct energy.
Muhamad Amani   +6 more
wiley   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

GKIN: a tool for drawing genetic networks [PDF]

open access: yesNetwork Biology, 2012
We present GKIN, a simulator and a comprehensive graphical interface where one can draw the model specification of reactions between hypothesized molecular participants in a gene regulatory and biochemical reaction network (or genetic network for short).
Jonathan Arnold   +2 more
doaj  

PROSTHETIC TRANSLATION: RETRANSLATIONS OF VIDEO GAME REMAKES AND REMASTERS REFUTE RETRANSLATION HYPOTHESIS

open access: yesHumanus: Jurnal Ilmiah Ilmu-ilmu Humaniora, 2019
Retranslation Hypothesis claims that retranslations tend to be more source-oriented than the first translations. Video game translation (VGT) refutes this hypothesis since retranslations in VGT, occuring on game remakes and remasters, are target oriented.
SF. Luthfie Arguby Purnomo   +2 more
doaj   +1 more source

BGS Sigma 2012 open source user guide [PDF]

open access: yes, 2013
The British Geological Survey began developing digital field mapping systems in 1989. However, it was apparent that the commercially available hardware was not suitable at that time.
Adlam, K.A.M., Bow, J., Turner, P.
core  

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

open access: yesAdvanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang   +9 more
wiley   +1 more source

齿轮类零件参数化设计系统的研究与开发

open access: yesJixie chuandong, 2009
Realizes automation which the gear class components design calculation and draws a chart, proposed take the parametrization design concept as the basis, uses which in AutoCAD inlays Visual LISP language and The DCL dialog box design language, realized ...
王鸿钧, 苏艳萍
doaj  

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