Results 181 to 190 of about 7,646 (295)

Outcomes After Kidney Transplantation in Antiglomerular Basement Membrane Disease. [PDF]

Kidney Int Rep
Traversat P, Dekervel M, Masset C, Bertrand D, Golbin L, Gatault P, Thierry A, Cornec-Le Gall E, Jaureguy M, Garrouste C, Anglicheau D, Chatelet V, Caillard S, Duval A, Rerolle JP, Planchais M, Duveau A, Duthe F, Augusto JF, Brilland B.   +19 more
europepmc   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Artificial intelligence to guide rituximab therapy in patients with phospholipase A2 receptor-associated membranous nephropathy. [PDF]

Clin Kidney J
Teisseyre M, Destere A, Cremoni M, Boyer-Suavet S, Karamé A, Corlu L, Duneau G, Poirier P, Lefevre S, Zorzi K, Fernandez C, Brglez V, Benzaken S, Favre G, Drici MD, Esnault VLM, Benito S, Seitz-Polski B.   +17 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Kidney Failure Risk Equation performance according to the etiology of chronic kidney disease in the CKD-CAREMEAU cohort. [PDF]

Clin Kidney J
Prouvot J, Ahmadpoor P, Clemmer E, Garo F, Pambrun E, Cariou S, Reboul P, Messikh Z, Moranne O.   +8 more
europepmc   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Blocking Sphingosine 1-phosphate Metabolism With Fingolimod Prevents the Progression of Vascular Smooth Muscle Cells Calcification in Chronic Kidney Disease. [PDF]

J Cell Physiol
Skafi N, Pelletier S, Soulage CO, Nahle S, Da Cruz BO, Othmani R, Briolay A, Reibel S, Vitale N, Hamade E, Badran B, Magne D, Buchet R, Stockler-Pinto MB, Fouque D, Mebarek S, Brizuela L.   +16 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Erratum to "Discordant Results Between Creatinine- and Cystatin C-based Equations for Estimating GFR" [<i>Kidney International Reports</i> Volume 10, Issue 4, April 2025, Pages 1248-1259]. [PDF]

Kidney Int Rep
Delanaye P, Flamant M, Vidal-Petiot E, Björk J, Nyman U, Grubb A, Bakker SJL, de Borst MH, van Londen M, Derain-Dubourg L, Rule AD, Eriksen BO, Melsom T, Sundin PO, Ebert N, Schaeffner E, Hansson M, Littmann K, Larsson A, Stehlé T, Cavalier E, Bukabau JB, Sumaili EK, Yayo E, Mariat C, Moranne O, Christensson A, Lanot A, Pottel H.   +28 more
europepmc   +1 more source