Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment
A novel orally drug‐probiotic co‐delivery system designated as Rh‐YBS for UC treatment, which highlights three innovations: (i) YPs involves colonic submucosa delivery via M cells; (ii) Rh (drug) promotes the colonization and growth of BS (probiotic) in the colon.
Lingqiang Li+21 more
wiley +1 more source
Perspectives of adult advanced pre-dialysis chronic kidney disease patients about kidney replacement therapy in three referral hospitals in Rwanda. [PDF]
Shumbusho G+15 more
europepmc +1 more source
OBSERVATIONS CONCERNING THE USE OF LYMPH FOR EXTRACORPOREAL DIALYSIS
H Sarles+4 more
openalex +1 more source
Hydrogels hold great potential as candidates for next‐generation epidermal electronics; however, an unresolved issue remains: the differentiation and selection of sensing modes in hydrogel sensors. This study integrates series‐parallel conductive nanosheet configurations into an ultra‐soft hydrogel, resulting in enhanced signal intensity and ...
Shitao Shi+9 more
wiley +1 more source
Exploring the Interplay Between Kidney Dysfunction and Cardiovascular Disease. [PDF]
Yadav R+8 more
europepmc +1 more source
A Supramolecular Material for Controlling Kiwifruit Bacterial Canker
The matrine‐5‐methylsalicylic acid salt (MOS) is reported for its excellent antibacterial activity against Pseudomonas syringae pv. actinidiae (Psa), with advanced cell membrane penetration ability and strong affinities for potential targets. Furthermore, a nanosupramolecular delivery system MOS@hydroxypropyl‐beta‐cyclodextrin (HPCD) with improved ...
Xile Deng+9 more
wiley +1 more source
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang+10 more
wiley +1 more source
Elevated effluent lactate independently predicts the adverse outcomes of peritoneal dialysis associated peritonitis. [PDF]
Yu X+6 more
europepmc +1 more source
Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod+9 more
wiley +1 more source
Managing the failing renal allograft: navigating a complex topography. [PDF]
Kendrick EA.
europepmc +1 more source