Results 71 to 80 of about 934,602 (387)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Association between baseline intact parathyroid hormone levels, COVID-19 severity, and long-term outcomes in patients undergoing hemodialysis: A multicenter retrospective study

Український Журнал Нефрології та Діалізу, 2023
The COVID-19 pandemic poses unique challenges for vulnerable populations, including patients undergoing maintenance hemodialysis (HD). This study explores the relationship between baseline intact parathyroid hormone (iPTH) levels and COVID-19 severity ...
L. Snisar, А. Rysyev, I. Poperechnyi, V. Filonov, T. Ostapenko, V. Marchenko, V. Dzhur   +6 more
doaj   +1 more source

Improving dialysis adherence for high risk patients using automated messaging: Proof of concept [PDF]

, 2017
Comorbidities and socioeconomic barriers often limit patient adherence and self-management with hemodialysis. Missed sessions, often associated with communication barriers, can result in emergency dialysis and avoidable hospitalizations.
An, T., Groenendyk, J., Patel, K., Peters, R., Polites, G., Ross, W. R, Som, A.   +6 more
core   +2 more sources

Overall and Site-Specific Cancer Mortality in Patients on Dialysis and after Kidney Transplant.

Journal of the American Society of Nephrology, 2019
Background Patients with ESRD have a substantially increased cancer risk, but few studies have examined the patterns of cancer mortality along a patient's journey from dialysis to transplantation.
E. Au, J. Chapman, J. Craig, W. Lim, A. Teixeira-Pinto, S. Ullah, S. McDonald, G. Wong   +7 more
semanticscholar   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Peritoneal dialysis in older adults: evaluation of clinical, nutritional, metabolic outcomes, and quality of life [PDF]

, 2018
The number of older adults requiring dialysis is increasing worldwide, whereas the use of peritoneal dialysis (PD) in this population is lower respect to younger patients, despite the theoretical advantages of PD respect to hemodialysis.
Aceto, Paola, Amabile, MARIA IDA, Bargagli, Matteo, Gnerre Musto, Tania, Group on Geriatric Nephrology of the Italian Society of Nephrology (SIN), Study, Lai, Carlo, Lai, Silvia, Martinez, Andrea, Mastroluca, Daniela, Molfino, Alessio, Testorio, Massimo   +10 more
core   +1 more source

Care Practices for Patients With Advanced Kidney Disease Who Forgo Maintenance Dialysis

JAMA Internal Medicine, 2019
Importance Although maintenance dialysis is a treatment choice with potential benefits and harms, little is known about care practices for patients with advanced chronic kidney disease who forgo this treatment.
S. Wong, L. Mcfarland, Chuan-Fen Liu, Ryan Laundry, P. Hebert, A. O'Hare   +5 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Effects of hemodialysis therapy on sit-to-walk characteristics in end stage renal disease patients [PDF]

, 2012
Patients with end stage renal diseases (ESRD) undergoing hemodialysis (HD) have high morbidity and mortality due to multiple causes; one of which is dramatically higher fall rates than the general population.
Abdel-Rahman, Emaad, Lach, John, Lockhart, Thurmon, Soangra, Rahul   +3 more
core   +2 more sources