Results 171 to 180 of about 319,180 (281)

Self‐Driving Laboratory Optimizes the Lower Critical Solution Temperature of Thermoresponsive Polymers

Advanced Intelligent Discovery, EarlyView.
A low‐cost, self‐driving laboratory is developed to democratize autonomous materials discovery. Using this "frugal twin" hardware architecture with Bayesian optimization, the platform rapidly converges to target lower critical solution temperature (LCST) values while self‐correcting from off‐target experiments, demonstrating an accessible route to data‐
Guoyue Xu, Renzheng Zhang, Tengfei Luo
wiley   +1 more source

Unforeseen risks due to the use of fluorinated materials for per- and polyfluoroalkyl substance removal. [PDF]

Nat Commun
Liu S, Letcher RJ, Diamond ML, Blum A, Chen D.   +4 more
europepmc   +1 more source

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

American Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan, Yang Liu, Heng‐Huan Lee, Wei Wang, Joseph McIntosh, Yijing Li, Jovanny Vargas, Yue Fei, Sairah Ahmed, Lukas M. Simon, Michael Wang   +10 more
wiley   +1 more source

Electromyographic Activation of the Pectoralis Major and Triceps Brachii Muscles During Standard, Diamond, and Wide Hand Position Push-Ups. [PDF]

Muscles
Intziegianni K, Katsamis E, Michaelides M, Parpa K.   +3 more
europepmc   +1 more source

Enhancing protein structure prediction: evaluating the role of amino acid physicochemical features in homology search. [PDF]

Brief Bioinform
Akbari Roknabadi S, Ahmadiyan H, Wong L, Koohi S.   +3 more
europepmc   +1 more source

Fabrication of Terahertz Fresnel Zone Plates via Ultraprecision Mechanical Processing. [PDF]

Micromachines (Basel)
Chen M, Wang J, Fang F.
europepmc   +1 more source

Predicted no effect concentrations of antifungals for wastewater management and agricultural use. [PDF]

Front Toxicol
Gil D, José S, Ascenso A, Babič MN, Segal E, Meletiadis J, Gangneux JP, Weiskerger CJ, Solo-Gabriele HM, Valério E, Brandão J.   +10 more
europepmc   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

Angewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

Context-dependent translation inhibition as a cancer therapeutic modality. [PDF]

Nat Commun
Diamond PD, Sauer PV, Holm M, Swanson-Swett CJ, Ferguson L, Bratset NM, Wienker GW, Sim JS, Adams HK, Kenner L, Meyers M, Gygi D, Könst ZA, Bahmanyar SS, Hamann LG, Schuller AP.   +15 more
europepmc   +1 more source

Magnetization Plateau of the Distorted Diamond Spin Chain

Magnetization Plateau of the Distorted Diamond Spin Chain
The frustrated quantum spin system on the distorted diamond chain lattice is investigated using the numerical diagonalization of finite- size clusters and the level spectroscopy analysis. In the previous work this system was revealed to exhibit the 1/3 magnetization plateau due to two different mechanisms depending on the coupling parameters, and the ...
openaire