Results 121 to 130 of about 222,963 (298)

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Form and load transfer aspects of foundation systems: Case‐based implementation and adaptation for buildings

Deep Underground Science and Engineering, EarlyView.
Upon conceptualization of structural behavior, foundations in terms of their form are divided into linear (1D), planar (2D), and volumetric (3D). Regarding the load transfer mechanisms, linear foundation systems are considered vector‐acting, planar foundations are divided into section and surface‐acting, and volumetric ones are recognized as block ...
Abolfazl Eslami, Amirhossein Ebrahimipour, Meysam Imani, Reza Imam, Pinqiang Mo   +4 more
wiley   +1 more source

Investigation on hard‐rock breaking performance and auxiliary mechanism of picks assisted with both‐sided high‐pressure water jets

Deep Underground Science and Engineering, EarlyView.
This paper investigates the high‐pressure water jet‐pick combined rock‐breaking mode (HPC), which employs high‐pressure water jets to precut grooves on both sides of the picks. The rock‐breaking patterns and performance of the HPC method are obtained, and the auxiliary rock‐breaking mechanism of water jet grooving is revealed.
Jingjing Lu, Jiancheng Xiao, Hui Zhou, Xiao Ma, Congcong Hou, Jian Cui, Fujian Yang   +6 more
wiley   +1 more source

Seismic analysis and design of tunnels within fault ground: A review

Deep Underground Science and Engineering, EarlyView.
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang, Yujing Jiang, Xuepeng Zhang, Yuyong Jiao, Ningbo Li, Xiao Wang, Bo Li   +6 more
wiley   +1 more source

Self‐Maintained Thermal Charging Cells for the Efficient Harvesting of Waste Heat at Elevated Temperatures

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Thermal charging cells (TCS) face two main challenges that limit their practical applications: 1) Still lacking the systems suitable for operation under higher temperature environments, and 2) there are limitations in the self‐sustaining performance of continuous discharge under temperature differences, which holds critical significance for the real ...
Tingting Meng, Yimin Xuan, Yunjie Xiong
wiley   +1 more source

Fluoro‐Functionalized Polyether Electrolytes Enabling High‐Energy‐Density Solid‐State Lithium‐Metal Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fluoro‐functionalized polyether electrolytes, which combine fluorine‐ and ether‐containing groups, achieve enhanced oxidative stability, high ionic conductivity, and superior interfacial stability. Due to their non‐flammability, remarkable flexibility, ease of processing, and design versatility, polymer‐based electrolytes containing polyethers have ...
Nannan Geng, Chenkai Lu, Wenbei Li, Qianxin Liu, Zixuan Zhou, Tao Yang, Yin Cui, Guobin Zhang, Xidong Lin   +8 more
wiley   +1 more source

Enhancing Anode‐Free Lithium Metal Batteries: A Lightweight MPTS‐MXene Current Collector for Superior Performance and Energy Density

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study introduces an MPTS‐modified MXene current collector for anode‐free lithium metal batteries (AFLMBs). A key advantage of MPTS‐MXene is its ultralight weight, only 15% as heavy as standard copper per unit volume. Its special layered structure and Si‐O rich surface help lithium deposit smoothly and flat, while forming a protective layer that ...
Jiawei Ren, Jiayi Zhang, Jingchao Zhang, Jianbo Li, Yonas Tsegaye Megra, Jianchuan Wang, Yong Du, Rong Huang, Yi Cui, Chenguang Liu, Li Yang   +10 more
wiley   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

Low‐Cost Friction‐Based Force‐Limiting Connection With Reduced Sensitivity to Machining Tolerances and Accelerated Repairability

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT This paper presents a novel yet practical friction‐based structural component design for low‐damage earthquake‐resistant structures. The proposed connection design is based on a conventional slotted‐bolted configuration with the novelty being the use of loose steel washer plates to establish the friction‐sliding interface.
Kaixin Chen, Georgios Tsampras, Chung‐Che Chou, Huang‐Zuo Lin, Chi‐Jeng Wu, Alvaro Córdova, Chia‐Ming Uang, Shih‐Ho Chao   +7 more
wiley   +1 more source