Results 71 to 80 of about 43,467 (247)

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

open access: yesAdvanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho   +13 more
wiley   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

open access: yesAdvanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian   +12 more
wiley   +1 more source

Congenital Nemaline Myopathy

open access: yesPediatric Neurology Briefs, 1994
A female neonate with a rapidly fatal course of nemaline myopathy is reported from the University of Siena, Italy.
J Gordon Millichap
doaj   +1 more source

Multiscale Design of Anion Exchange Membrane‐Based Seawater Electrolysis for Sustainable Hydrogen Production

open access: yesAdvanced Energy Materials, EarlyView.
Direct seawater electrolysis using anion exchange membranes is emerging as a promising route for sustainable hydrogen production. This review summarizes multiscale design strategies from seawater chemistry and OER–ClER selectivity to catalysts, membranes, MEAs, cells, stacks, and system integration, providing a roadmap toward selective, durable, and ...
Chiho Kim   +7 more
wiley   +1 more source

Long Noncoding RNAs in Aortic Dissection: Mechanistic Roles and Therapeutic Potential

open access: yesAGING MEDICINE, EarlyView.
Aortic dissection (AD) involves vascular inflammation, VSMC dysfunction, and ECM degradation. LncRNAs regulate AD progression via ceRNA networks, with great potential as diagnostic biomarkers and therapeutic targets, while further clinical validation is needed.
Chao Chang   +5 more
wiley   +1 more source

A Compact, High‐Performance, and Deformation‐Resilient Trielectrode Electrostatic Soft Pump for Soft Robotics

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Existing soft pumps often require tradeoffs between performance and compatibility with soft robotic systems. The proposed trielectrode electrostatic soft pump addresses these limitations through an innovative driving mechanism. Its design, which includes a trielectrode configuration and the use of compliant materials, improves operational efficiency ...
Yangqiao Lin   +10 more
wiley   +1 more source

Eventration of the Diaphragm

open access: yesAsian Journal of Surgery, 2006
Eventration of the diaphragm (ED) is defined as the abnormal elevation of the diaphragm. Although asymptomatic ED may be amenable to conservative treatment, symptomatic ED in children, either congenital or acquired, may require surgical treatment.
Tuğrul Tiryaki   +2 more
openaire   +3 more sources

A Soft Robotic Finger With Deep Learning‐Enhanced Tactile Sensing for Texture and Softness Recognition

open access: yesAdvanced Intelligent Systems, EarlyView.
Inspired by human touch, a tendon‐driven soft robotic finger combines multimodal tactile sensing and deep learning to simultaneously perceive texture and softness on deformable surfaces. A CNN‐LSTM model fuses pressure, accelerometer, and gyroscope signals to accurately classify material properties, achieving up to 95.4% texture and 97.0% softness ...
Gorkem Anil Al   +3 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Assessing the Impact of Manual Therapy Techniques on the Diaphragm and Deep Trunk Muscle Exercises for Stabilisation and Level of Pain in the Lumbar Spine of COPD Patients [PDF]

open access: yesRehabilitacja Medyczna
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide. Its main symptoms include cough, shortness of breath, sputum retention and reduced exercise tolerance.
Anna Olbrych   +2 more
doaj   +1 more source

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