Results 101 to 110 of about 67,649 (311)

AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease [PDF]

, 2017
Pompe disease (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extensive glycogen storage and impaired autophagy.
Alvino, Filomena Grazia, Auricchio, Alberto, Ballabio, Andrea, Carrella, Alessandra, De Leonibus, Elvira, Diez-roux, Graciana, Gatto, Francesca, Iacobellis, Francesca, Nusco, Edoardo, Parenti, Giancarlo, Polishchuk, Elena, Polishchuk, Roman, Rossi, Barbara, Tarallo, Antonietta   +13 more
core   +1 more source

Diaphragm muscle adaptations in health and disease

Drug Discovery Today: Disease Models, 2019
Breathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors.
Matthew J, Fogarty, Gary C, Sieck
openaire   +3 more sources

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source

Comparative Studies of Hind Limb and Diaphragm Muscles of mdx Mice [PDF]

Histological, immunocytochemical and immunochemical characteristics of diaphragm muscle from mdx and control mice (14-days to 12-months of age) were compared to those of their hind limb muscles.
Anna Fidzianska, Irena Niebrqj-dobosz, Zofia Glinka   +2 more
core  

Early changes in rat diaphragm biology with mechanical ventilation [PDF]

, 2003
To better characterize the effects of 24-hour mechanical ventilation on diaphragm, the expression of myogenic transcription factors, myosin heavy chains, and sarcoplasmic/endoplasmic reticulum calcium-ATPase pumps was examined in rats.
Cadot, Pascal, De Paepe, Kristel, Decramer, Marc, Gayan-Ramirez, Ghislaine, Rácz, Gábor Z., Testelmans, Dries, Wuytack, Frank, Zádor, Ernő   +7 more
core   +1 more source

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

Diaphragm Skeletal Muscle Preparation v1 [PDF]

, 2018
For isolated diaphragm skeletal muscle preparation,each hemi-diaphragm segment was transferred to an organ bath, and the dissected tissue was tied up to a holder fixed at the bottom of the glass organ bath, while the upper extremity of the tissue was fixed to a force transducer.The contraction of the diaphragm muscle was induced by transmural ...
openaire   +1 more source

The anatomical knowledge of Namibian school children

Anatomical Sciences Education, EarlyView.
Abstract The public has limited knowledge of key organs and anatomical structures. The lack of anatomical knowledge and understanding can hinder time to access healthcare, quality of care, and treatment outcomes. The current study investigated the anatomical knowledge among Namibian children by comparing 8 school grades—4 to 12, which covers children ...
Adam M. Taylor, Lojandrie Kirsten, Luigi Sedda, Quenton Wessels   +3 more
wiley   +1 more source

Tactile feedback display with spatial and temporal resolutions. [PDF]

, 2013
We report the electronic recording of the touch contact and pressure using an active matrix pressure sensor array made of transparent zinc oxide thin-film transistors and tactile feedback display using an array of diaphragm actuators made of an ...
Brochu, Paul, Jing, Yi, Kalajian, Michael, Kargar, Alireza, Lewis, Brian W, Li, Chun, Nguyen, Truong, Niu, Xiaofan, Park, Namseok, Pei, Qibing, Sun, Ke, Sun, Zhelin, Vishniakou, Siarhei, Wang, Deli, Yang, Muchuan   +14 more
core   +2 more sources

Assessment of Inspiratory Muscle Activation using Surface Diaphragm Mechanomyography and Crural Diaphragm Electromyography

2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018
The relationship between surface diaphragm mechanomyography (sMMGdi), as a noninvasive measure of inspiratory muscle mechanical activation, and crural diaphragm electromyography (oesEMGdi), as the invasive gold standard measure of diaphragm electrical activation, had not previously been examined.
Manuel, Lozano-Garcia, Leonardo, Sarlabous, John, Moxham, Gerrard F, Rafferty, Abel, Torres, Caroline J, Jolley, Raimon, Jane   +6 more
openaire   +3 more sources