Results 171 to 180 of about 67,649 (311)

Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction

Experimental Physiology, EarlyView.
Abstract Mechanical ventilation (MV) is a life‐saving intervention applied to critically ill patients. A common consequence of MV is ventilator‐induced diaphragm dysfunction (VIDD), which is characterized by significant diaphragm atrophy and reduced contractile function. Older patients who receive MV are more likely to develop VIDD, have worse recovery,
P. H. C. Mesquita, J. L. Halle, J. D. Fuqua, B. F. Miller   +3 more
wiley   +1 more source

PPMO-based exon skipping therapy improves respiratory function in the <i>mdx</i> mouse model of Duchenne muscular dystrophy. [PDF]

Mol Ther Nucleic Acids
Biswas DD, Rodriguez MYH, El Haddad L, Hoffmann G, Copson E, Mayman S, Jose J, Lang S, Chen O, Dela Pena A, Levin E, Abdelbarr M, Slyne A, ElMallah MK.   +13 more
europepmc   +1 more source

Ultrasound Evaluation of Diaphragmatic and Intercostal Muscle Function as an Indicator of COPD Severity: A Prospective Cross-Sectional Study. [PDF]

Int J Chron Obstruct Pulmon Dis
Dong Z, Zhao M, Zheng S, Gu H, Cao N, Sun X, Ge J, Yan X, Ye J, Huang B.   +9 more
europepmc   +1 more source

Imposed expiratory resistance, dynamic hyperinflation and locomotor power and fatigue

Experimental Physiology, EarlyView.
Abstract Expiratory flow limitation results in dynamic hyperinflation, dyspnoea and premature exercise intolerance. We aimed to measure whether expiratory resistance reduces locomotor power via limiting maximal voluntary motor activity, exacerbating muscle fatigue, or both.
Jonathan Cunha, Antoinette Domingo, Fred W. Kolkhorst, Harry B. Rossiter, Daniel T. Cannon   +4 more
wiley   +1 more source

Cerebral haemodynamic responses to inspiratory muscle work

Experimental Physiology, EarlyView.
Abstract Fatiguing inspiratory work has been shown to evoke a sympathetically mediated reflex that has systemic cardiovascular consequences, including increases in heart rate and blood pressure and a decrease in resting limb vascular conductance. Moreover, the response to this reflex appears to be attenuated in females compared with males.
Andrew H. Ramsook, Morgan A. Hughes, Wyatt W. Pruter, Kevin L. Webb, Ali Ataie, Chad C. Wiggins, Gabrielle A. Dillon, Sarah E. Baker, Michael J. Joyner   +8 more
wiley   +1 more source

Characterizing core muscle morphometry in postpartum women with pelvic girdle pain and asymptomatic subjects: a comparative cross-sectional study. [PDF]

PeerJ
Lin Z, Chen B, Chen R, Chen X, Hou Y, Liu Y, Lin L, Lin Z, Wang X, Zeng C.   +9 more
europepmc   +1 more source

Pattern of extra-diaphragmatic respiratory muscle activity during exercise in patients with unilateral diaphragm dysfunction. [PDF]

Physiol Rep
Rodrigues A, Louvaris Z, Dacha S, Pereira MC, Gojevic T, Schaeffer MR, Janssens L, Janssens W, Reid WD, Gayan-Ramirez G, Testelmans D, Brochard L, Gosselink R, Langer D.   +13 more
europepmc   +1 more source

Muscle fibre type shift in COPD: Adaptive, maladaptive or a bit of both?

Experimental Physiology, EarlyView.
Jacob Peter Hartmann, Hannah G. Caldwell, Ulrik Winning Iepsen   +2 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Diaphragm Contraction Pressure Index: A New Forecasting Indicator for Weaning from Mechanical Ventilation. [PDF]

Int J Gen Med
Zhang P, Jiang H, Li Z, Zhou Q, Wu J, Wang M, Wu J, Jiang X.   +7 more
europepmc   +1 more source