Results 11 to 20 of about 67,649 (311)
Diaphragm muscle sarcopenia in aging mice [PDF]
Experimental Gerontology, 2013 Sarcopenia, defined as muscle weakness and fiber atrophy, of respiratory muscles such as the diaphragm (DIAm) has not been well characterized. The DIAm is the main inspiratory muscle and knowledge of DIAm sarcopenia is important for establishing the effects of aging on respiratory function.
Sarah M, Greising +4 more
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Peripheral and respiratory muscle impairment during murine acute lung injury
Physiological Reports, 2022 Acute respiratory distress syndrome is associated with skeletal muscle compromise, which decreases survival and impairs functional capacity. A comparative analysis of peripheral and respiratory muscles' atrophy and dysfunction in acute lung injury (ALI ...
Martín Angulo +13 more
doaj +1 more source
Annals of Intensive Care, 2020 Background Inappropriate ventilator assist plays an important role in the development of diaphragm dysfunction. Ventilator under-assist may lead to muscle injury, while over-assist may result in muscle atrophy.
L. H. Roesthuis +5 more
doaj +1 more source
Нервно-мышечные болезни, 2022 Background. As motor neuron disease (MND) and myasthenia gravis (MG) progress, the respiratory muscles are involved in the pathological process with the development of respiratory failure, which is one of the main causes of death.
Yu. N. Rushkevich +3 more
doaj +1 more source
Breathing: Motor Control of Diaphragm Muscle [PDF]
Physiology, 2018 Breathing occurs without thought but is controlled by a complex neural network with a final output of phrenic motor neurons activating diaphragm muscle fibers (i.e., motor units). This review considers diaphragm motor unit organization and how they are controlled during breathing as well as during expulsive behaviors.
Fogarty, Matthew J. +2 more
openaire +3 more sources
Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy. [PDF]
PLoS ONE, 2015 Various therapeutic approaches have been studied for the treatment of Duchenne muscular dystrophy (DMD), but none of these approaches have led to significant long-term effects in patients.
Kelly M Gutpell +2 more
doaj +1 more source
Indices of Defective Autophagy in Whole Muscle and Lysosome Enriched Fractions From Aged D2-mdx Mice
Frontiers in Physiology, 2021 Duchenne muscular dystrophy (DMD) is a fatal, progressive muscle disease caused by the absence of functional dystrophin protein. Previous studies in mdx mice, a common DMD model, identified impaired autophagy with lysosomal insufficiency and impaired ...
Swathy Krishna +5 more
doaj +1 more source
Functional Interaction of Pelvic Floor, Diaphragm and Trunk Muscles among Men with Prostate Cancer
Baltic Journal of Sport and Health Sciences, 2018 Research background and hypothesis. The absolute dominance of the isolated muscle presentation as the first and last word in muscular anatomy leaves the current generation of therapists unlikely to think any other way (Myers, 2009 ...
Brigita Zachovajevienė +4 more
doaj +1 more source
Determinants of inspiratory muscle strength in healthy humans [PDF]
, 2014 We investigated 1) the relationship between the baseline and inspiratory muscle training (IMT) induced increase in maximal inspiratory pressure (PI,max) and 2) the relative contributions of the inspiratory chest wall muscles and the diaphragm (Poes/Pdi ...
Brown, PI, Johnson, MA, Sharpe, GR
core +1 more source
Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]
, 2014 Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora +7 more
core +1 more source