Results 61 to 70 of about 67,649 (311)
Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length
eLife, 2017 Muscle fiber length is nearly uniform within a muscle but widely different among different muscles. We show that Abelson tyrosine-protein kinase 2 (Abl2) has a key role in regulating myofiber length, as a loss of Abl2 leads to excessively long myofibers ...
Jennifer K Lee +2 more
doaj +1 more source
α-smooth muscle actin is not a marker of fibrogenic cell activity in skeletal muscle fibrosis. [PDF]
PLoS ONE, 2018 α-Smooth muscle actin (α-SMA) is used as a marker for a subset of activated fibrogenic cells, myofibroblasts, which are regarded as important effector cells of tissue fibrogenesis.
Wanming Zhao +3 more
doaj +1 more source
Autonomic Responses Associated with Severe Gagging Elicited by Stimulation of the Superior Laryngeal Nerve in Rats [PDF]
, 2012 Tactile stimulation of the pharyngo-laryngeal region elicits severe gagging, which is characterized by simultaneous contraction of the costal diaphragm and abdominal muscles.
Koga Tomoshige, Yamagata Ryuzo
core +1 more source
BLOC: Buildable and Linkable Organ on a Chip
Advanced Materials Technologies, EarlyView.We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura +7 more
wiley +1 more source
JCI Insight, 2022 Muscle weakness and wasting are defining features of cancer-induced cachexia. Mitochondrial stress occurs before atrophy in certain muscles, but the possibility of heterogeneous responses between muscles and across time remains unclear.
Luca J. Delfinis +14 more
doaj +1 more source
Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats [PDF]
PeerJ, 2017 Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Therapeutic options are still scarce. We hypothesized that cachexia-induced muscle oxidative stress may be attenuated in response to treatment ...
Anna Salazar-Degracia +4 more
doaj +2 more sources
Mapping the cortical representation of the lumbar paravertebral muscles [PDF]
, 2007 Objective: The aim of this study was to map the cortical representation of the lumbar spine paravertebral (LP) muscles in healthy subjects. Methods: Transcranial magnetic stimulation (TMS) was employed to map the cortical representations of the LP ...
A.V. Nowicky +32 more
core +1 more source
Optogenetic diaphragm muscle activation in mice
The FASEB Journal, 2021 Breathing impairments are the leading cause of morbidity and mortality across all forms of neuromuscular disease. When voluntarily diaphragm activation is insufficient, clinical options include mechanical ventilation or electrical stimulation via intramuscular wires. Here we tested the hypothesis that an optogenetic approach would enable light to serve
Ethan Benevides +3 more
openaire +1 more source
Advanced Materials Technologies, EarlyView.This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
wiley +1 more source
Physiological ReportsThe present study was designed to examine the effect of trans‐spinal magnetic stimulation on bilateral respiratory and forelimb muscles in healthy subjects.
Ming‐Yue Ren +3 more
doaj +1 more source