Results 41 to 50 of about 21,121 (164)

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Diaphragm Ultrasonography Reveals Progressive Changes in Diaphragmatic Function, Morphology, and Muscle Trophism During Invasive Mechanical Ventilation in Children

Journal of Clinical Ultrasound, EarlyView.
Diaphragm ultrasonography detected progressive structural and functional deterioration in mechanically ventilated children. Prolonged invasive mechanical ventilation and neuromuscular blocking agent use were associated with ventilator‐induced diaphragmatic dysfunction, highlighting ultrasound as a valuable bedside tool to support individualized ...
Juliana Bezerra dos Santos, Emmerson Carlos Franco de Farias, Mary Lucy Ferraz Maia Fiuza de Mello, Rodrigo Santiago Barbosa Rocha   +3 more
wiley   +1 more source

Construction of a Non‐Invasive Predictive Model Based on PIVKA‐II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley   +1 more source

Reduced diaphragmatic function during term labor and its association with second stage of labor: an intrapartum ultrasound study

Frontiers in Physiology
BackgroundTo investigate differences in diaphragmatic function between women undergoing term labor and healthy non-pregnant women, and to analyze the correlation between diaphragmatic function and duration of the second stage of labor.
Chunfeng Liu, Shijie Zhang, Huilan Hong, Yongjian Chen, Guorong Lyu, Guorong Lyu   +5 more
doaj   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Diaphragmatic assessment in COPD patients by different modalities

Egyptian Journal of Chest Disease and Tuberculosis, 2017
Background: The study of diaphragm is considered a key point in the evaluation of COPD patients. Ultrasonography can be used for assessment of the site, structure and the motion of the diaphragm, assessment of excursion and thickness and also diagnosis ...
Amal A. Abd El Aziz, Rabab A. Elwahsh, Gehan A. Abdelaal, Mohammed S. Abdullah, Rehab A. Saad   +4 more
doaj   +1 more source

Ultrasonographic evaluation of diaphragmatic thickness and movement for assessment of diaphragmatic dysfunction in COPD patients

The Egyptian Journal of Bronchology
Abstract Backgrounds Chronic obstructive pulmonary disease (COPD) is often ascribed to the disparity that exists between ventilatory loading and diaphragmatic function. The principal factor contributing to this imbalance is the mechanical difficulties brought about by pulmonary hyperinflation.
Eman Mohamed Dahma, Walaa Mowafy El-lawaty, Dalia Ezzat Shaarawy, Mohammed Mahmoud Dawoud, Wafaa Saleh El-Shimy   +4 more
openaire   +2 more sources

Reduced Phrenic CMAP Amplitudes in Obesity Despite Preserved Diaphragm Ultrasound Measures

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Phrenic nerve conduction studies (NCS) are regularly used in the evaluation of neuromuscular respiratory dysfunction; however, the impact of body mass index (BMI) on phrenic compound muscle action potential (CMAP) amplitudes remains poorly characterized. We evaluated the relationship between BMI and phrenic CMAP amplitudes in
Andrea J. Boon, Elie Naddaf, Grayson Beecher   +2 more
wiley   +1 more source

Inspiration Time: The Ultrasound Variable Necessary to Study the Diaphragm Functionality. A Cross-Sectional Controlled Study

SAGE Open Nursing
Introduction The diaphragm is considered the main inspiratory muscle, and as such, its assessment is crucial in patients with respiratory pathology. It is known that the contractile capacity of a muscle is determined by strength, length, and the duration
Teresa E Fernández-Pardo PT, MSc, PhD student, Maria Jesús Rodríguez-Nieto PhD, Mercedes Furió-Valverde PT, María García-Arrabé PT, MSc, PhD, Ana Mallo-Lopez PT, MSc, PhD student, Ignacio Mahillo-Fernández PhD, Germán Peces-Barba Romero PhD   +6 more
doaj   +1 more source

Diaphragmatic ultrasound findings correlate with dyspnea, exercise tolerance, health-related quality of life and lung function in patients with fibrotic interstitial lung disease

BMC Pulmonary Medicine, 2019
Background Fibrotic interstitial lung disease (FILD) patients are typically dyspneic and exercise-intolerant with consequent impairment of health-related quality of life (HRQoL).
Pauliane Vieira Santana, Leticia Zumpano Cardenas, André Luis Pereira de Albuquerque, Carlos Roberto Ribeiro de Carvalho, Pedro Caruso   +4 more
doaj   +1 more source