Results 41 to 50 of about 493,894 (311)

Assessing water filtration and safe storage in households with young children of HIV-positive mothers: a randomized, controlled trial in Zambia. [PDF]

, 2012
BACKGROUND: Unsafe drinking water presents a particular threat to people living with HIV/AIDS (PLHIV) due to the increased risk of opportunistic infections, diarrhea-associated malabsorption of essential nutrients, and increased exposure to untreated ...
Clasen, Thomas, Peletz, R, Simunyama Martin, Sarenje Kelvin, Simunyama, Martin, Sarenje, Kelvin, Suzanne Filteau, Thomas Clasen, Rachel Peletz (132102), Filteau, S, Clasen Thomas, Paul Kelly, Martin Simunyama, Kathy Baisley (132119), Martin Simunyama (132107), Baisley, Kathy, Thomas Clasen (132131), Paul Kelly (95510), Simunyama, M, Peletz, Rachel, Clasen, T, Kathy Baisley, Filteau Suzanne, Filteau, Suzanne, Rachel Peletz, Kelvin Sarenje, Kelvin Sarenje (132113), Suzanne Filteau (132124), Peletz Rachel, Kelly Paul, Baisley Kathy, Baisley, K, Kelly, Paul, Sarenje, K, Kelly, P   +34 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Treatment of traveler's diarrhea - clinical review

Journal of Education, Health and Sport, 2020
Travelers’ diarrhea is defined as the passage of three or more unformed stools per 24 hours plus at least one additional symptom such as nausea, vomiting, abdominal cramps, fever, blood/mucus in the stools, or fecal urgency that develop while abroad or ...
Karol Mazur, Dominik Machaj, Dominika Mazur, Aneta Asztabska, Alicja Płaczek   +4 more
doaj   +1 more source

Prevalence of Enteropathogenic Viruses and Molecular Characterization of group A rotavirus among Children with Diarrhea in Dar es Salaam Tanzania. [PDF]

, 2007
Different groups of viruses have been shown to be responsible for acute diarrhea among children during their first few years of life. Epidemiological knowledge of viral agents is critical for the development of effective preventive measures, including ...
Matee, Mecky I., Langeland, Nina, Kirsti Vainio, Maselle, Samwel Y, Sabrina J Moyo, Jesse Kitundu, Samwel Y Maselle, Gro, N., Myrmel Helge, Mecky I Matee, Moyo, Sabrina John, Kirsti, Vainio, Myrmel, H., Langeland Nina, Kirsti, V., Maselle, Samwel Y., Njølstad, Gro, Kitundu, J., Langeland, N., Matee, Mecky I, Maselle Samwel Y, Gro Njolstad, Matee, M.I., Vainio Kirsti, Nina Langeland, Maselle, S.Y., Myrmel, Helge, Moyo, S.J., Kitundu, Jesse, Kitundu Jesse, Matee Mecky I, Vainio, Kirsti, Helge Myrmel, Njolstad Gro, Moyo Sabrina J, Gro, Njolstad, Moyo, Sabrina J   +36 more
core   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Diarrhea in peripheral stem cell transplant recipients: a developing country’s experience

Journal of Infection in Developing Countries, 2014
Introduction: We aimed to determine the frequency and microbiological causes of diarrhea occurring during the first 100 days in allogeneic (allo-) and autologous (auto-) stem cell transplantation (SCT) patients.
Cigdem Pala, Leylagul Kaynar, Ruksan Buyukoglan, Fatih Kurnaz, Gokhan Metan, Suleyman Yazar, Suleyman Durmaz, Ayse Sakioglu, Sedar Sivgin, Bulent Eser, Ali Unal, Mustafa Cetin   +11 more
doaj   +1 more source

Improving Knowledge, Attitude, and Perception towards Childhood Diarrhea Using Interactive Discussion in Kulon Progo Community

Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement), 2021
Introduction: Diarrhea is still a leading cause of death in the world in children, especially in children under 5 years. Diarrhea is a contagious disease with relatively high morbidity and mortality rates. Rotavirus is a cause of diarrhea in children and
Jarir At Thobari, Wahyu Damayanti, Asal Wahyuni Erlin Mulyadi, Jonathan Hasian Haposan, Annisa Setiyaningrum, Shofya Indraguna, Sutarman S, Nailatul Arifah, Anggit Dewi Rahayu, Faridatun Khasanah, Al Razi Sena, Yati Soenaro   +11 more
doaj   +1 more source

The use of probiotics to prevent diarrhea in young children attending child care centers: a review [PDF]

, 2010
The incidence of diarrheal disease in children has been reduced because of public health measures, improved hygiene, and a better understanding of nutrition. However, it remains a particular problem where young children come into close contact with other
Binns, C., Mi Kyung Lee, Lee, M., Colin Binns, Lee, M.K., Binns, Colin   +5 more
core   +1 more source